LITAF Antikörper

Produktnummer ABIN7261431

Produktdetails anti-LITAF Antikörper

Target: LITAF (Lipopolysaccharide-Induced Tumor Necrosis Factor-alpha Factor (LITAF))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LITAF Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Spezifität: This antibody ist KO validated.

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Güteklasse: KO Validated

Immunogen: Recombinant fusion protein of human LITAF (NP_004853.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000 IHC 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu LITAF

Target: LITAF (Lipopolysaccharide-Induced Tumor Necrosis Factor-alpha Factor (LITAF))

Andere Bezeichnung: LITAF (LITAF Produkte)

Synonyme: PIG7 antikoerper, SIMPLE antikoerper, TP53I7 antikoerper, EET-1 antikoerper, Pig7 antikoerper, TNF-alpha antikoerper, 3222402J11Rik antikoerper, C85531 antikoerper, N4WBP3 antikoerper, TBX1 antikoerper, lipopolysaccharide induced TNF factor antikoerper, lipopolysaccharide-induced TNF factor antikoerper, LPS-induced TN factor antikoerper, LITAF antikoerper, Litaf antikoerper

Hintergrund: Lipopolysaccharide is a potent stimulator of monocytes and macrophages, causing secretion of tumor necrosis factor-alpha (TNF-alpha) and other inflammatory mediators. This gene encodes lipopolysaccharide-induced TNF-alpha factor, which is a DNA-binding protein and can mediate the TNF-alpha expression by direct binding to the promoter region of the TNF-alpha gene. The transcription of this gene is induced by tumor suppressor p53 and has been implicated in the p53-induced apoptotic pathway. Mutations in this gene cause Charcot-Marie-Tooth disease type 1C (CMT1C) and may be involved in the carcinogenesis of extramammary Paget's disease (EMPD). Multiple alternatively spliced transcript variants have been found for this gene.

Molekulargewicht:

Observed_MW: 20 kDa

Calculated_MW: 15 kDa/17 kDa/23 kDa

Gen-ID: 9516

UniProt: Q99732

Pathways: Cellular Response to Molecule of Bacterial Origin