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NUAK1 Antikörper

NUAK1 Reaktivität: Human, Ratte WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7259682
  • Target Alle NUAK1 Antikörper anzeigen
    NUAK1 (NUAK Family, SNF1-Like Kinase, 1 (NUAK1))
    Reaktivität
    • 56
    • 27
    • 8
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Ratte
    Wirt
    • 52
    • 4
    • 1
    Kaninchen
    Klonalität
    • 56
    • 1
    Polyklonal
    Konjugat
    • 22
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser NUAK1 Antikörper ist unkonjugiert
    Applikation
    • 27
    • 25
    • 18
    • 13
    • 13
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Produktmerkmale
    Polyclonal Antibody
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant fusion protein of human NUAK1 (NP_055655.1).
    Isotyp
    IgG
    Top Product
    Discover our top product NUAK1 Primärantikörper
  • Applikationshinweise
    WB 1:200-1:2000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    NUAK1 (NUAK Family, SNF1-Like Kinase, 1 (NUAK1))
    Andere Bezeichnung
    NUAK1 (NUAK1 Produkte)
    Synonyme
    ARK5 antikoerper, AU014801 antikoerper, AW494241 antikoerper, B230104P22Rik antikoerper, Omphk1 antikoerper, NUAK family kinase 1 antikoerper, NUAK family, SNF1-like kinase, 1 antikoerper, NUAK1 antikoerper, Nuak1 antikoerper
    Hintergrund
    NUAK family SNF1-like kinase 1also known asAMPK-related protein kinase 5(ARK5) is anenzymethat in humans is encoded by theNUAK1gene. Serine/threonine-protein kinase involved in various processes such as cell adhesion, regulation of cell ploidy and senescence, cell proliferation and tumor progression. Phosphorylates ATM, CASP6, LATS1, PPP1R12A and p53/TP53. Acts as a regulator of cellular senescence and cellular ploidy by mediating phosphorylation of 'Ser-464' of LATS1, thereby controlling its stability. Controls cell adhesion by regulating activity of the myosin protein phosphatase 1 (PP1) complex. Acts by mediating phosphorylation of PPP1R12A subunit of myosin PP1: phosphorylated PPP1R12A then interacts with 14-3-3, leading to reduced dephosphorylation of myosin MLC2 by myosin PP1.
    Molekulargewicht

    Observed_MW: 74 kDa

    Calculated_MW: 23 kDa/74 kDa

    Gen-ID
    9891
    UniProt
    O60285
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