NUAK1 Antikörper
Kurzübersicht für NUAK1 Antikörper (ABIN7238549)
Target
Alle NUAK1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Produktmerkmale
- Polyclonal Antibody
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Aufreinigung
- Affinity purification
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Immunogen
- Synthetic peptide of human NUAK1
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Isotyp
- IgG
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anti-NUAK Family, SNF1-Like Kinase, 1 (NUAK1) (AA 1-30), (N-Term) antibody
NUAK1 Reaktivität: Human, Maus, Hamster WB, IHC (p) Wirt: Kaninchen Polyclonal RB3520 unconjugated
anti-NUAK Family, SNF1-Like Kinase, 1 (NUAK1) (AA 604-634), (C-Term) antibodyNUAK1 Reaktivität: Human, Maus WB, IHC (p) Wirt: Kaninchen Polyclonal RB3521 unconjugated
anti-NUAK Family, SNF1-Like Kinase, 1 (NUAK1) (AA 1-661) antibodyNUAK1 Reaktivität: Human WB, IF Wirt: Maus Polyclonal unconjugated
anti-NUAK Family, SNF1-Like Kinase, 1 (NUAK1) (AA 451-550) antibodyNUAK1 Reaktivität: Human ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-NUAK Family, SNF1-Like Kinase, 1 (NUAK1) (Internal Region) antibodyVerified NUAK1 Reaktivität: Human ELISA, IF, FACS Wirt: Ziege Polyclonal unconjugated
anti-NUAK Family, SNF1-Like Kinase, 1 (NUAK1) (C-Term) antibodyNUAK1 Reaktivität: Human, Maus, Ratte WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-NUAK Family, SNF1-Like Kinase, 1 (NUAK1) (AA 362-661) antibodyNUAK1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-NUAK Family, SNF1-Like Kinase, 1 (NUAK1) (AA 404-651) antibodyNUAK1 Reaktivität: Maus WB, IHC Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- IHC 1:25-1:100
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.6 mg/mL
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Buffer
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- NUAK1 (NUAK Family, SNF1-Like Kinase, 1 (NUAK1))
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Andere Bezeichnung
- NUAK1
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Hintergrund
- NUAK family SNF1-like kinase 1also known asAMPK-related protein kinase 5(ARK5) is anenzymethat in humans is encoded by theNUAK1gene. Serine/threonine-protein kinase involved in various processes such as cell adhesion, regulation of cell ploidy and senescence, cell proliferation and tumor progression. Phosphorylates ATM, CASP6, LATS1, PPP1R12A and p53/TP53. Acts as a regulator of cellular senescence and cellular ploidy by mediating phosphorylation of 'Ser-464' of LATS1, thereby controlling its stability. Controls cell adhesion by regulating activity of the myosin protein phosphatase 1 (PP1) complex. Acts by mediating phosphorylation of PPP1R12A subunit of myosin PP1: phosphorylated PPP1R12A then interacts with 14-3-3, leading to reduced dephosphorylation of myosin MLC2 by myosin PP1.
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NCBI Accession
- NP_055655
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UniProt
- O60285
Target
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