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MAP3K3 Antikörper

MAP3K3 Reaktivität: Human, Maus, Ratte IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7009253
  • Target Alle MAP3K3 Antikörper anzeigen
    MAP3K3 (Mitogen-Activated Protein Kinase Kinase Kinase 3 (MAP3K3))
    Reaktivität
    • 35
    • 32
    • 17
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 43
    • 4
    Kaninchen
    Klonalität
    • 35
    • 12
    Polyklonal
    Konjugat
    • 30
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MAP3K3 Antikörper ist unkonjugiert
    Applikation
    • 37
    • 20
    • 8
    • 7
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC)
    Produktmerkmale
    Polyclonal Antibody
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant fusion protein of human MAP3K3 (NP_976226.1).
    Isotyp
    IgG
    Top Product
    Discover our top product MAP3K3 Primärantikörper
  • Applikationshinweise
    IHC 1:100-1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    MAP3K3 (Mitogen-Activated Protein Kinase Kinase Kinase 3 (MAP3K3))
    Andere Bezeichnung
    MAP3K3 (MAP3K3 Produkte)
    Synonyme
    MAPKKK3 antikoerper, MEKK3 antikoerper, AW548911 antikoerper, Mekk3 antikoerper, mKIAA4031 antikoerper, mitogen activated protein kinase kinase kinase 3 antikoerper, mitogen-activated protein kinase kinase kinase 3 antikoerper, Map3k3 antikoerper, MAP3K3 antikoerper, map3k3 antikoerper
    Hintergrund
    This gene product is a 626-amino acid polypeptide that is 96.5 % identical to mouse Mekk3. Its catalytic domain is closely related to those of several other kinases, including mouse Mekk2, tobacco NPK, and yeast Ste11. Northern blot analysis revealed a 4.6-kb transcript that appears to be ubiquitously expressed. This protein directly regulates the stress-activated protein kinase (SAPK) and extracellular signal-regulated protein kinase (ERK) pathways by activating SEK and MEK1/2 respectively, it does not regulate the p38 pathway. In cotransfection assays, it enhanced transcription from a nuclear factor kappa-B (NFKB)-dependent reporter gene, consistent with a role in the SAPK pathway. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
    Gen-ID
    4215
    UniProt
    Q99759
    Pathways
    MAPK Signalweg
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