PTPRJ Antikörper

Produktnummer ABIN7255177

Produktdetails anti-PTPRJ Antikörper

Target: PTPRJ (Protein tyrosine Phosphatase, Receptor Type, J (PTPRJ))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PTPRJ Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human PTPRJ (NP_002834.3).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:200-1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PTPRJ

Target: PTPRJ (Protein tyrosine Phosphatase, Receptor Type, J (PTPRJ))

Andere Bezeichnung: PTPRJ (PTPRJ Produkte)

Synonyme: HAAP antikoerper, CD148 antikoerper, DEP1 antikoerper, HPTPeta antikoerper, R-PTP-ETA antikoerper, SCC1 antikoerper, AI450271 antikoerper, BET antikoerper, Byp antikoerper, DEP-1 antikoerper, PTPbeta2 antikoerper, Ptpb2 antikoerper, RPTPJ antikoerper, Scc-1 antikoerper, Scc1 antikoerper, PTPRJ antikoerper, acid phosphatase 1 antikoerper, protein tyrosine phosphatase, receptor type J antikoerper, protein tyrosine phosphatase, receptor type, J antikoerper, ACP1 antikoerper, PTPRJ antikoerper, Ptprj antikoerper, EUBREC_2762 antikoerper

Hintergrund: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes, including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region containing five fibronectin type III repeats, a single transmembrane region, and a single intracytoplasmic catalytic domain, and thus represents a receptor-type PTP. This protein is present in all hematopoietic lineages, and was shown to negatively regulate T cell receptor signaling possibly through interfering with the phosphorylation of Phospholipase C Gamma 1 and Linker for Activation of T Cells. This protein can also dephosphorylate the PDGF beta receptor, and may be involved in UV-induced signal transduction. Multiple transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht:

Observed_MW: 260 kDa

Calculated_MW: 57 kDa/145 kDa

Gen-ID: 5795

UniProt: Q12913

Pathways: EGFR Signaling Pathway, Platelet-derived growth Factor Receptor Signaling