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Protein tyrosine Phosphatase, Receptor Type, J Produkte

(Protein tyrosine Phosphatase, Receptor Type, J (PTPRJ))
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes, including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region containing five fibronectin type III repeats, a single transmembrane region, and a single intracytoplasmic catalytic domain, and thus represents a receptor-type PTP. This protein is present in all hematopoietic lineages, and was shown to negatively regulate T cell receptor signaling possibly through interfering with the phosphorylation of Phospholipase C Gamma 1 and Linker for Activation of T Cells. This protein can also dephosphorylate the PDGF beta receptor, and may be involved in UV-induced signal transduction. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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Protein tyrosine Phosphatase, Receptor Type, J Antikörper

High quality antibodies with extensive validation data.

Protein tyrosine Phosphatase, Receptor Type, J ELISA Kits

Reliable ELISA kits for a wide range of species.

Protein tyrosine Phosphatase, Receptor Type, J Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene Protein tyrosine Phosphatase, Receptor Type, J Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Mouse
Applikation WB, IHC, IP, ICC
Validierungen
  • (8)
Kat. Nr. ABIN7441778
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, ICC, IHC (p), IHC (fro)
Validierungen
  • (4)
Kat. Nr. ABIN7440614
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC, FACS, ICC, Neut
Validierungen
  • (4)
Kat. Nr. ABIN7193256
Menge 0.1 mg
Datenblatt Datenblatt

Empfohlene Protein tyrosine Phosphatase, Receptor Type, J ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6969755
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6958961
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN4882596
Menge 96 tests
Datenblatt Datenblatt

Empfohlene Protein tyrosine Phosphatase, Receptor Type, J Proteine

Produkt
Reaktivität
Source
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Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7124686
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1316873
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3094860
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren Protein tyrosine Phosphatase, Receptor Type, J Produkten

Bilotta, Dattilo, DAgostino, Belviso, Scalise, Bilotta, Gaudio, Paduano, Perrotti, Florio, Fusco, Iuliano, Trapasso: "A novel splice variant of the protein tyrosine phosphatase PTPRJ that encodes for a soluble protein involved in angiogenesis." in: Oncotarget, Vol. 8, Issue 6, pp. 10091-10102, (2018) (PubMed).

Spring, Fournier, Lapointe, Chabot, Roussy, Pommey, Stagg, Royal: "The protein tyrosine phosphatase DEP-1/PTPRJ promotes breast cancer cell invasion and metastasis." in: Oncogene, Vol. 34, Issue 44, pp. 5536-47, (2015) (PubMed).

Spring, Lapointe, Caron, Langlois, Royal: "Phosphorylation of DEP-1/PTPRJ on threonine 1318 regulates Src activation and endothelial cell permeability induced by vascular endothelial growth factor." in: Cellular signalling, Vol. 26, Issue 6, pp. 1283-93, (2014) (PubMed).

Rollin, Pouplard, Gratacap, Leroux, May, Aupart, Gouilleux-Gruart, Payrastre, Gruel: "Polymorphisms of protein tyrosine phosphatase CD148 influence FcγRIIA-dependent platelet activation and the risk of heparin-induced thrombocytopenia." in: Blood, Vol. 120, Issue 6, pp. 1309-16, (2012) (PubMed).

Ambarus, Krausz, van Eijk, Hamann, Radstake, Reedquist, Tak, Baeten: "Systematic validation of specific phenotypic markers for in vitro polarized human macrophages." in: Journal of immunological methods, Vol. 375, Issue 1-2, pp. 196-206, (2012) (PubMed).

Stepanek, Kalina, Draber, Skopcova, Svojgr, Angelisova, Horejsi, Weiss, Brdicka: "Regulation of Src family kinases involved in T cell receptor signaling by protein-tyrosine phosphatase CD148." in: The Journal of biological chemistry, Vol. 286, Issue 25, pp. 22101-12, (2011) (PubMed).

Llinàs, Lázaro, de Salort, Matesanz-Isabel, Sintes, Engel: "Expression profiles of novel cell surface molecules on B-cell subsets and plasma cells as analyzed by flow cytometry." in: Immunology letters, Vol. 134, Issue 2, pp. 113-21, (2010) (PubMed).

Cabezón, Sintes, Llinàs, Benitez-Ribas: "Analysis of HLDA9 mAbs on plasmacytoid dendritic cells." in: Immunology letters, Vol. 134, Issue 2, pp. 167-73, (2010) (PubMed).

Sacco, Tinti, Palma, Ferrari, Nardozza, Hooft van Huijsduijnen, Takahashi, Castagnoli, Cesareni: "Tumor suppressor density-enhanced phosphatase-1 (DEP-1) inhibits the RAS pathway by direct dephosphorylation of ERK1/2 kinases." in: The Journal of biological chemistry, Vol. 284, Issue 33, pp. 22048-58, (2009) (PubMed).

Dong, Shahsafaei, Dorfman: "CD148 and CD27 are expressed in B cell lymphomas derived from both memory and naïve B cells." in: Leukemia & lymphoma, Vol. 43, Issue 9, pp. 1855-8, (2003) (PubMed).

Synonyme und alternative Namen zu Protein tyrosine Phosphatase, Receptor Type, J

acid phosphatase 1 (ACP1), protein tyrosine phosphatase, receptor type J (PTPRJ), protein tyrosine phosphatase, receptor type, J (Ptprj), protein tyrosine phosphatase, receptor type, J (PTPRJ), protein tyrosine phosphatase, receptor type, J (EUBREC_2762), AI450271, BET, Byp, CD148, DEP-1, DEP1, HAAP, HPTPeta, Ptpb2, PTPbeta2, PTPRJ, R-PTP-ETA, RPTPJ, Scc-1, SCC1, Scc1

Bezeichner auf Proteinebene für Protein tyrosine Phosphatase, Receptor Type, J

  • LMW-PTP
  • LMW-PTPase
  • acid phosphatase of erythrocyte
  • adipocyte acid phosphatase
  • cytoplasmic phosphotyrosyl protein phosphatase
  • low molecular weight cytosolic acid phosphatase
  • low molecular weight phosphotyrosine protein phosphatase
  • protein tyrosine phosphatase
  • red cell acid phosphatase 1
  • CD148 antigen
  • DEP-1
  • HPTP eta
  • R-PTP-J
  • density-enhanced phosphatase 1
  • human density enhanced phosphatase-1
  • protein tyrosine phosphatase, receptor type, J polypeptide
  • protein-tyrosine phosphatase eta
  • protein-tyrosine phosphatase receptor type J
  • receptor-type tyrosine-protein phosphatase eta
  • susceptibility to colon cancer 1, mouse, homolog of
  • HPTP beta-like tyrosine phosphatase
  • R-PTP-eta
  • colon tumor susceptibility 1
  • susceptibility to colon cancer 1
  • density enhanced phosphatase-1
  • supporting-cell antigen
  • protein tyrosine phosphatase, receptor type, J
  • receptor-type tyrosine-protein phosphatase eta-like
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