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ERK1/2 Antikörper (pTyr204)

MAPK1/3 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC (p), IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7250725
  • Target Alle ERK1/2 (MAPK1/3) Antikörper anzeigen
    ERK1/2 (MAPK1/3) (Mitogen-Activated Protein Kinase 1/3 (MAPK1/3))
    Bindungsspezifität
    • 56
    • 40
    • 30
    • 30
    • 16
    • 12
    • 12
    • 10
    • 8
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pTyr204
    Reaktivität
    • 199
    • 169
    • 166
    • 23
    • 23
    • 18
    • 7
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 143
    • 58
    • 4
    Kaninchen
    Klonalität
    • 139
    • 66
    Polyklonal
    Konjugat
    • 99
    • 12
    • 9
    • 9
    • 8
    • 8
    • 8
    • 8
    • 8
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Dieser ERK1/2 Antikörper ist unkonjugiert
    Applikation
    • 157
    • 65
    • 51
    • 50
    • 50
    • 37
    • 25
    • 22
    • 22
    • 13
    • 7
    • 4
    • 4
    • 3
    • 2
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
    Produktmerkmale
    Phosphorylated antibody
    Aufreinigung
    Affinity purification
    Immunogen
    Synthesized peptide derived from human ERK 1/2 around the phosphorylation site of Tyr204
    Isotyp
    IgG
    Top Product
    Discover our top product MAPK1/3 Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:10000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    ERK1/2 (MAPK1/3) (Mitogen-Activated Protein Kinase 1/3 (MAPK1/3))
    Andere Bezeichnung
    ERK 1/2 (MAPK1/3 Produkte)
    Synonyme
    erk1/2 antikoerper, mitogen-activated protein kinase antikoerper, erk1/2 antikoerper
    Hintergrund
    Involved in both the initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors such as ELK1. Phosphorylates EIF4EBP1, required for initiation of translation. Phosphorylates microtubule-associated protein 2 (MAP2). Phosphorylates SPZ1 (By similarity). Phosphorylates heat shock factor protein 4 (HSF4) and ARHGEF2.Acts as a transcriptional repressor. Binds to a [GC]AAA[GC] consensus sequence. Repress the expression of interferon gamma-induced genes. Seems to bind to the promoter of CCL5, DMP1, IFIH1, IFITM1, IRF7, IRF9, LAMP3, OAS1, OAS2, OAS3 and STAT1. Transcriptional activity is independent of kinase activity.
    Molekulargewicht

    Observed_MW: 44+42 kDa

    Calculated_MW: 43 kDa

    UniProt
    P27361, P28482
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