HUWE1 Antikörper

Produktnummer ABIN7248203

Produktdetails anti-HUWE1 Antikörper

Target: HUWE1 (HECT, UBA and WWE Domain Containing 1, E3 Ubiquitin Protein Ligase (HUWE1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HUWE1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Antigen affinity purification

Immunogen: Synthetic peptide of human HUWE1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:10-1:50, ELISA 1:5000-1:10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.8 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu HUWE1

Target: HUWE1 (HECT, UBA and WWE Domain Containing 1, E3 Ubiquitin Protein Ligase (HUWE1))

Andere Bezeichnung: HUWE1 (HUWE1 Produkte)

Synonyme: ARF-BP1 antikoerper, HECTH9 antikoerper, HSPC272 antikoerper, Ib772 antikoerper, LASU1 antikoerper, MULE antikoerper, URE-B1 antikoerper, UREB1 antikoerper, 5430439H10Rik antikoerper, AU041296 antikoerper, Arf-bp1 antikoerper, C430014N20Rik antikoerper, C80292 antikoerper, Gm1718 antikoerper, Mule antikoerper, Ureb1 antikoerper, HUWE1 antikoerper, si:dkey-242a8.2 antikoerper, Huwe1 antikoerper, mule antikoerper, ib772 antikoerper, lasu1 antikoerper, ureb1 antikoerper, hecth9 antikoerper, arf-bp1 antikoerper, hspc272 antikoerper, HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase antikoerper, HECT, UBA and WWE domain containing 1 antikoerper, E3 ubiquitin-protein ligase HUWE1 antikoerper, HUWE1 antikoerper, Huwe1 antikoerper, huwe1 antikoerper, LOC100123214 antikoerper, LOC100380641 antikoerper

Hintergrund: This gene encodes a protein containing a C-terminal HECT (E6AP type E3 ubiquitin protein ligase) domain that functions as an E3 ubiquitin ligase. The encoded protein is required for the ubiquitination and subsequent degradation of the anti-apoptotic protein Mcl1 (myeloid cell leukemia sequence 1 (BCL2-related)). This protein also ubiquitinates the p53 tumor suppressor, core histones, and DNA polymerase beta. Mutations in this gene are associated with Turner type X-linked syndromic mental retardation.

UniProt: Q7Z6Z7