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Doublecortin Antikörper

DCX Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7248044
  • Target Alle Doublecortin (DCX) Antikörper anzeigen
    Doublecortin (DCX)
    Reaktivität
    • 110
    • 73
    • 67
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 101
    • 12
    • 2
    • 2
    Kaninchen
    Klonalität
    • 96
    • 21
    Polyklonal
    Konjugat
    • 64
    • 9
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Doublecortin Antikörper ist unkonjugiert
    Applikation
    • 74
    • 40
    • 32
    • 13
    • 12
    • 11
    • 9
    • 8
    • 8
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Produktmerkmale
    Polyclonal Antibody
    Aufreinigung
    Antigen affinity purification
    Immunogen
    Synthetic peptide of human DCX
    Isotyp
    IgG
    Top Product
    Discover our top product DCX Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1.3 mg/mL
    Buffer
    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    Doublecortin (DCX)
    Andere Bezeichnung
    DCX (DCX Produkte)
    Synonyme
    DCX antikoerper, DBCN antikoerper, DC antikoerper, LISX antikoerper, SCLH antikoerper, XLIS antikoerper, Dbct antikoerper, 18C15.5 antikoerper, doublecortin antikoerper, DCX antikoerper, Dcx antikoerper
    Hintergrund
    This gene encodes a member of the doublecortin family. The protein encoded by this gene is a cytoplasmic protein and contains two doublecortin domains, which bind microtubules. In the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation. The encoded protein appears to direct neuronal migration by regulating the organization and stability of microtubules. In addition, the encoded protein interacts with LIS1, the regulatory gamma subunit of platelet activating factor acetylhydrolase, and this interaction is important to proper microtubule function in the developing cortex. Mutations in this gene cause abnormal migration of neurons during development and disrupt the layering of the cortex, leading to epilepsy, cognitive disability, subcortical band heterotopia ("double cortex" syndrome) in females and lissencephaly ("smooth brain" syndrome) in males. Multiple transcript variants encoding different isoforms have been found for this gene.
    Molekulargewicht

    Observed_MW: Refer to figures

    Calculated_MW: 49 kDa

    UniProt
    O43602
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