Glutaminase Antikörper

Produktnummer ABIN7247984

Produktdetails anti-Glutaminase Antikörper

Target: Glutaminase (GLS)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Glutaminase Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Antigen affinity purification

Immunogen: Synthetic peptide of human GLS

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200, ELISA 1:5000-1:10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.02 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Glutaminase

Target: Glutaminase (GLS)

Andere Bezeichnung: GLS (GLS Produkte)

Synonyme: Glut antikoerper, RATGLUT antikoerper, gls antikoerper, si:dz87i4.2 antikoerper, wu:fa97e05 antikoerper, GA antikoerper, PAG antikoerper, AAD20 antikoerper, GAC antikoerper, GAM antikoerper, GLS1 antikoerper, KGA antikoerper, AI314027 antikoerper, 6330442B14 antikoerper, B230365M23Rik antikoerper, CG8772 antikoerper, CG8872 antikoerper, Dmel\\CG42708 antikoerper, Dmel_CG8772 antikoerper, BA3155 antikoerper, glutaminase antikoerper, glutaminase b antikoerper, Glutaminase antikoerper, glutaminase kidney isoform, mitochondrial antikoerper, Gls antikoerper, GLS antikoerper, gls antikoerper, glsb antikoerper, glsA2 antikoerper, glsA-2 antikoerper, Arnit_3113 antikoerper, Celal_2913 antikoerper, Celly_0289 antikoerper, Weevi_2101 antikoerper, Mesop_4683 antikoerper, LOC100069617 antikoerper

Hintergrund: GLS,also named as GLS1 and KIAA0838,belongs to the glutaminase family. It catalyzes the first reaction in the primary pathway for the renal catabolism of glutamine. Glutaminase-,glutamate-,and taurine-immunoreactive neurons develop neurofibrillary tangles in Alzheimer's disease.The glutaminase band in AA/C1 cells is more intense than in HT29 cells,in accordance with measurements of glutaminase activity,and had the same molecular mass of approx. 63 kDa. The bands for both cell lines are clearly different in size from both rat liver glutaminase (58 kDa) and rat kidney glutaminase (65 kDa). It also reveals a molecular weight of 83-84 kDa as a phosphate-dependent glutaminase. It has 3 isoforms named as KGA,GAM,GAC.

Molekulargewicht:

Observed_MW: Refer to figures

Calculated_MW: 73 kDa

UniProt: O94925

Pathways: Feeding Behaviour, Dicarboxylic Acid Transport, Warburg Effekt