PCSK5 Antikörper

Produktnummer ABIN7004184

Produktdetails anti-PCSK5 Antikörper

Target: PCSK5 (Proprotein Convertase Subtilisin/kexin Type 5 (PCSK5))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PCSK5 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Antigen affinity purification

Immunogen: Fusion protein of human PCSK5

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:30-1:150, ELISA 1:5000-1:10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.6 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PCSK5

Target: PCSK5 (Proprotein Convertase Subtilisin/kexin Type 5 (PCSK5))

Andere Bezeichnung: PCSK5 (PCSK5 Produkte)

Synonyme: PC5 antikoerper, PC6 antikoerper, PC6A antikoerper, SPC6 antikoerper, subtilase antikoerper, PC5/6A antikoerper, PC5A antikoerper, b2b1549Clo antikoerper, b2b585Clo antikoerper, Pc5 antikoerper, fur2 antikoerper, spc6 antikoerper, spc6A antikoerper, MGC98915 antikoerper, PCSK5 antikoerper, pc6 antikoerper, spc6a antikoerper, pcsk5 antikoerper, zgc:165659 antikoerper, proprotein convertase subtilisin/kexin type 5 antikoerper, proprotein convertase subtilisin/kexin type 5 S homeolog antikoerper, proprotein convertase subtilisin/kexin type 5b antikoerper, PCSK5 antikoerper, Pcsk5 antikoerper, pcsk5.S antikoerper, LOC528098 antikoerper, pcsk5 antikoerper, pcsk5b antikoerper

Hintergrund: This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER. It then sorts to the trans-Golgi network where a second autocatalytic event takes place and the catalytic activity is acquired. This encoded protein is widely expressed and one of the seven basic amino acid-specific members which cleave their substrates at single or paired basic residues. It mediates posttranslational endoproteolytic processing for several integrin alpha subunits and is thought to process prorenin, pro-membrane type-1 matrix metalloproteinase and HIV-1 glycoprotein gp160. Alternative splicing results in multiple transcript variants, some of which encode distinct isoforms, including a protease packaged into dense core granules (PC5A) and a type 1 membrane bound protease (PC5B).

UniProt: Q92824

Pathways: Neurotrophin Signalübertragung, Regulation of Systemic Arterial Blood Pressure by Hormones