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C9ORF116 Antikörper

C9ORF116 Reaktivität: Human ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7246424
  • Target Alle C9ORF116 Produkte
    C9ORF116 (Chromosome 9 Open Reading Frame 116 (C9ORF116))
    Reaktivität
    • 20
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 20
    Kaninchen
    Klonalität
    • 20
    Polyklonal
    Konjugat
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser C9ORF116 Antikörper ist unkonjugiert
    Applikation
    • 20
    • 13
    • 13
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC)
    Produktmerkmale
    Polyclonal Antibody
    Aufreinigung
    Antigen affinity purification
    Immunogen
    Fusion protein of human C9orf116
    Isotyp
    IgG
  • Applikationshinweise
    IHC 1:50-1:300, ELISA 1:5000-1:10000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.96 mg/mL
    Buffer
    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    C9ORF116 (Chromosome 9 Open Reading Frame 116 (C9ORF116))
    Andere Bezeichnung
    C9orf116 (C9ORF116 Produkte)
    Synonyme
    PIERCE1 antikoerper, RbEST47 antikoerper, Rbest47 antikoerper, chromosome 9 open reading frame 116 antikoerper, RIKEN cDNA 1700007K13 gene antikoerper, chromosome ssa24 open reading frame, human C9orf116 antikoerper, chromosome 11 open reading frame, human C9orf116 antikoerper, C9orf116 antikoerper, 1700007K13Rik antikoerper, cssa24h9orf116 antikoerper, C11H9orf116 antikoerper
    Hintergrund
    C9orf116, also known as PIERCE1. PIERCE1 is an important p53 target gene contributing to normal DNA damage response and may play crucial roles in maintaining genomic integrity against genotoxic stresses, including UVC irradiation. PIERCE1 exists as two alternatively spliced isoforms and is predominantly expressed in human small cell lung cancer. PIERCE1 knockdown induces down-regulation of proapoptotic genes including Ei24, Apaf1 and PTEN, suggesting that PIERCE1 is a proapoptotic gene. It is helpful for in-depth understanding of p53 pathways and the design of new cancer therapies.
    UniProt
    Q5BN46
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