ZFAND5 Antikörper

Produktnummer ABIN7245737

Produktdetails anti-ZFAND5 Antikörper

Target: ZFAND5 (Zinc Finger, AN1-Type Domain 5 (ZFAND5))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ZFAND5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Antigen affinity purification

Immunogen: Full length fusion protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.4 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu ZFAND5

Target: ZFAND5 (Zinc Finger, AN1-Type Domain 5 (ZFAND5))

Andere Bezeichnung: ZFAND5 (ZFAND5 Produkte)

Synonyme: 2310057A04Rik antikoerper, 5830475F03Rik antikoerper, AA415485 antikoerper, Za20d2 antikoerper, Zfp216 antikoerper, ZA20D2 antikoerper, ZFAND5A antikoerper, ZNF216 antikoerper, wu:fi29f06 antikoerper, za20d2l antikoerper, zgc:56057 antikoerper, za20d2 antikoerper, zfand5 antikoerper, zfand5-a antikoerper, zfand5-b antikoerper, zfand5a antikoerper, znf216 antikoerper, id:ibd2892 antikoerper, wu:fb16d02 antikoerper, wu:fc67h07 antikoerper, zgc:73363 antikoerper, zinc finger, AN1-type domain 5 antikoerper, zinc finger AN1-type containing 5 antikoerper, zinc finger, AN1-type domain 5b antikoerper, zinc finger AN1-type containing 5 L homeolog antikoerper, zinc finger, AN1-type domain 5a antikoerper, Zfand5 antikoerper, ZFAND5 antikoerper, zfand5b antikoerper, zfand5.L antikoerper, zfand5a antikoerper

Hintergrund: Involved in protein degradation via the ubiquitin-proteasome system. May act by anchoring ubiquitinated proteins to the proteasome. Plays a role in ubiquitin-mediated protein degradation during muscle atrophy. Plays a role in the regulation of NF-kappa-B activation and apoptosis. Inhibits NF-kappa-B activation triggered by overexpression of RIPK1 and TRAF6 but not of RELA. Inhibits also tumor necrosis factor (TNF), IL-1 and TLR4-induced NF-kappa-B activation in a dose-dependent manner. Overexpression sensitizes cells to TNF-induced apoptosis. Is a potent inhibitory factor for osteoclast differentiation.

Molekulargewicht:

Observed_MW: Refer to figures

Calculated_MW: 23 kDa

UniProt: O76080

Pathways: Platelet-derived growth Factor Receptor Signaling