ZFAND5 Antikörper (AA 121-213) (Alexa Fluor 350)

Produktnummer ABIN1693556

Produktdetails anti-ZFAND5 Antikörper (Alexa Fluor 350)

Target: ZFAND5 (Zinc Finger, AN1-Type Domain 5 (ZFAND5))

Bindungsspezifität: AA 121-213

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ZFAND5 Antikörper ist konjugiert mit Alexa Fluor 350

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat,Cow,Sheep,Pig,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ZFAND5

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu ZFAND5

Target: ZFAND5 (Zinc Finger, AN1-Type Domain 5 (ZFAND5))

Andere Bezeichnung: ZFAND5 (ZFAND5 Produkte)

Synonyme: 2310057A04Rik antikoerper, 5830475F03Rik antikoerper, AA415485 antikoerper, Za20d2 antikoerper, Zfp216 antikoerper, ZA20D2 antikoerper, ZFAND5A antikoerper, ZNF216 antikoerper, wu:fi29f06 antikoerper, za20d2l antikoerper, zgc:56057 antikoerper, za20d2 antikoerper, zfand5 antikoerper, zfand5-a antikoerper, zfand5-b antikoerper, zfand5a antikoerper, znf216 antikoerper, id:ibd2892 antikoerper, wu:fb16d02 antikoerper, wu:fc67h07 antikoerper, zgc:73363 antikoerper, zinc finger, AN1-type domain 5 antikoerper, zinc finger AN1-type containing 5 antikoerper, zinc finger, AN1-type domain 5b antikoerper, zinc finger AN1-type containing 5 L homeolog antikoerper, zinc finger, AN1-type domain 5a antikoerper, Zfand5 antikoerper, ZFAND5 antikoerper, zfand5b antikoerper, zfand5.L antikoerper, zfand5a antikoerper

Hintergrund:

Synonyms: ZA20D2, ZNF216, ZFAND5A, AN1-type zinc finger protein 5, Zinc finger A20 domain-containing protein 2, Zinc finger protein 216, ZFAND5

Background: Involved in protein degradation via the ubiquitin-proteasome system. May act by anchoring ubiquitinated proteins to the proteasome. Plays a role in ubiquitin-mediated protein degradation during muscle atrophy. Plays a role in the regulation of NF-kappa-B activation and apoptosis. Inhibits NF-kappa-B activation triggered by overexpression of RIPK1 and TRAF6 but not of RELA. Inhibits also tumor necrosis factor (TNF), IL-1 and TLR4-induced NF-kappa-B activation in a dose-dependent manner. Overexpression sensitizes cells to TNF-induced apoptosis. Is a potent inhibitory factor for osteoclast differentiation.

Gen-ID: 7763

UniProt: O76080

Pathways: Platelet-derived growth Factor Receptor Signaling