IFT74 Antikörper

Produktnummer ABIN7238834

Produktdetails anti-IFT74 Antikörper

Target: IFT74 (Intraflagellar Transport Protein 74 Homolog (IFT74))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IFT74 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Synthetic peptide of human IFT74

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.1 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu IFT74

Target: IFT74 (Intraflagellar Transport Protein 74 Homolog (IFT74))

Andere Bezeichnung: IFT74 (IFT74 Produkte)

Synonyme: CCDC2 antikoerper, DKFZp469F1522 antikoerper, 1700029H06Rik antikoerper, Ccdc2 antikoerper, Cmg1 antikoerper, b2b796Clo antikoerper, CMG-1 antikoerper, CMG1 antikoerper, intraflagellar transport protein 74/72 antikoerper, intraflagellar transport 74 antikoerper, intraflagellar transport protein 74 homolog antikoerper, IFT74 antikoerper, ift74 antikoerper, LOC100632007 antikoerper, LOC100649180 antikoerper, Ift74 antikoerper

Hintergrund: Capillary morphogenesis protein 1 (CMG1), also known as intraflagellar transport protein 74 (ITP74) or coiled-coil domain-containing protein 2 (CCDC2), is a 600 amino acid human homologue of IFT-71, a complex B protein supporting intraflagellar transport (IFT) in Chlamydomonas. CMG1 localizes to the cytoplasmic vesicle and is highly expressed in adult and fetal kidney and testis, with lower levels of expression in adult heart, placenta, lung, liver and pancreas, and in fetal heart, lung and liver. CMG1 has been suggested to have a role in the primary cilia of HUVEC, and it also functions as a transcriptional regulator of cyclin D2 in spermatocyte-derived cells.

Molekulargewicht: 69 kDa

NCBI Accession: NP_001092692

UniProt: Q96LB3

Pathways: Hedgehog Signalweg, Chromatin Binding