KNSTRN Antikörper

Produktnummer ABIN7233849

Produktdetails anti-KNSTRN Antikörper

Target: KNSTRN (Kinetochore-Localized Astrin/SPAG5 Binding Protein (KNSTRN))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KNSTRN Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Recombinant Human Small kinetochore-associated protein protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 2 mg/mL

Buffer: PBS with 0.05 % Proclin300 and 50 % glycerol, pH 7.4.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu KNSTRN

Target: KNSTRN (Kinetochore-Localized Astrin/SPAG5 Binding Protein (KNSTRN))

Andere Bezeichnung: C15orf23 (KNSTRN Produkte)

Synonyme: 1700025D04Rik antikoerper, C15orf23 antikoerper, D2Ertd750e antikoerper, SKAP antikoerper, Traf4af1 antikoerper, TRAF4AF1 antikoerper, kinetochore-localized astrin/SPAG5 binding antikoerper, kinetochore localized astrin/SPAG5 binding protein antikoerper, kinetochore-localized astrin/SPAG5 binding protein antikoerper, Knstrn antikoerper, KNSTRN antikoerper

Hintergrund: Essential component of the mitotic spindle required for faithful chromosome segregation and progression into anaphase . Promotes the metaphase-to-anaphase transition and is required for chromosome alignment, normal timing of sister chromatid segregation, and maintenance of spindle pole architecture. The astrin (SPAG5)-kinastrin (SKAP) complex promotes stable microtubule-kinetochore attachments. Required for kinetochore oscillations and dynamics of microtubule plus-ends during live cell mitosis, possibly by forming a link between spindle microtubule plus-ends and mitotic chromosomes to achieve faithful cell division.

Molekulargewicht:

Observed_MW: 35 kDa

Calculated_MW: 35 kDa

UniProt: Q9Y448

Pathways: M Phase