RHOT1 Antikörper (N-Term)

Produktnummer ABIN6992082

Produktdetails anti-RHOT1 Antikörper

Target: RHOT1 (Ras Homolog Gene Family, Member T1 (RHOT1))

Bindungsspezifität: AA 40-90, N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RHOT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Spezifität: RHOT1 antibody is human, mouse and rat reactive. At least three isoforms of RHOT1 are known to exist, this antibody will detect all three isoforms.

Aufreinigung: RHOT1 antibody is affinity chromatography purified via peptide column.

Immunogen: RHOT1 antibody was raised against a 15 amino acid peptide near the amino terminus of human RHOT1. The immunogen is located within amino acids 40 - 90 of RHOT1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: RHOT1 antibody can be used for detection of RHOT1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in rat samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: RHOT1 antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: RHOT1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu RHOT1

Target: RHOT1 (Ras Homolog Gene Family, Member T1 (RHOT1))

Andere Bezeichnung: RHOT1 (RHOT1 Produkte)

Synonyme: rhot1 antikoerper, zgc:55581 antikoerper, zgc:77063 antikoerper, wu:fd14e11 antikoerper, wu:fi14a05 antikoerper, arht2 antikoerper, miro-2 antikoerper, rasl antikoerper, ARHT1 antikoerper, MIRO-1 antikoerper, MIRO1 antikoerper, 2210403N23Rik antikoerper, AA415293 antikoerper, AF244542 antikoerper, AI834919 antikoerper, Arht1 antikoerper, C430039G08Rik antikoerper, Miro1 antikoerper, miro1 antikoerper, si:dkeyp-97g3.6 antikoerper, ras homolog family member T1a antikoerper, ras homolog family member T2 antikoerper, ras homolog family member T1 antikoerper, ras homolog family member T1 L homeolog antikoerper, rhot1a antikoerper, rhot2 antikoerper, RHOT1 antikoerper, rhot1 antikoerper, rhot1.L antikoerper, Rhot1 antikoerper, rhot1b antikoerper

Hintergrund: The Ras homolog family member T1 (RHOT) is an atypical Rho Ca2+-binding GTPase that localizes to the mitochondria (1). RHOT1, the related protein RHOT2, the adaptor protein Milton, and the PTEN induced putative kinase 1 (PINK1), form a complex that is involved in axonal transport of mitochondria (2,3). Both PINK1 and Parkin target RHOT1 for phosphorylation and degradation, causing the arrest of mitochondrial motility (4).

Molekulargewicht: Predicted: 76 kDa

Observed: 78 kDa

Gen-ID: 55288

NCBI Accession: NP_001028740

UniProt: Q8IXI2