LMX1B Antikörper (C-Term)
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- Target Alle LMX1B Antikörper anzeigen
- LMX1B (LIM Homeobox Transcription Factor 1, beta (LMX1B))
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Bindungsspezifität
- AA 280-330, C-Term
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser LMX1B Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
- Spezifität
- At least three isoforms are known to exist. This antibody is predicted to not cross-react with LMX1A.
- Aufreinigung
- LMX1B Antibody is affinity chromatography purified via peptide column.
- Immunogen
- Rabbit polyclonal LMX1B antibody was raised against a 17 amino acid peptide near the carboxy terminus of human LMX1B. The immunogen is located within amino acids 280 - 330 of LMX1B.
- Isotyp
- IgG
- Top Product
- Discover our top product LMX1B Primärantikörper
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- Applikationshinweise
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LMX1B antibody can be used for detection of LMX1B by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human and mouse samples and Immunofluorescence in human and mouse samples. All other applications and species not yet tested. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- LMX1B Antibody is supplied in PBS containing 0.02 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,4 °C
- Informationen zur Lagerung
- LMX1B antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- Target
- LMX1B (LIM Homeobox Transcription Factor 1, beta (LMX1B))
- Andere Bezeichnung
- LMX1B (LMX1B Produkte)
- Synonyme
- LMX1.2 antikoerper, NPS1 antikoerper, LMX antikoerper, LMX1 antikoerper, LMX1.1 antikoerper, lmx1b antikoerper, lmx1b.1 antikoerper, Xlmx1b antikoerper, lmx1b.2 antikoerper, LIM homeobox transcription factor 1 beta antikoerper, LIM homeobox transcription factor 1, beta b antikoerper, LIM homeobox transcription factor 1, beta, gene 1 S homeolog antikoerper, LIM homeobox transcription factor 1, beta a antikoerper, LMX1B antikoerper, Lmx1b antikoerper, lmx1bb antikoerper, lmx1b.1.S antikoerper, lmx1ba antikoerper
- Hintergrund
- LMX1B Antibody: The LIM homeobox transcription factor 1B (LMX1B) belongs to the LIM-homeodomain family. Members of this family are known to be important for pattern formation during development. LMX1B regulates mid-hindbrain patterning, LMX1B-null mice embryos have a severe reduction in the number of midbrain dopaminergic neurons compared to wild-type. While LMX1B appears to be important for both the development and the survival of dopamine neurons, the related LMX1A is crucial for the differentiation of these cells. However, LMX1A and LMX1B function cooperatively to regulated the proliferation, specification and differentiation of midbrain dopaminergic neuronal progenitors.
- Molekulargewicht
- 45 kDa
- Gen-ID
- 4010
- NCBI Accession
- NP_001167617
- UniProt
- O60663
- Pathways
- Dopaminergic Neurogenesis
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