ABCA7 Antikörper (N-Term)

Produktnummer ABIN6991700

Produktdetails anti-ABCA7 Antikörper

Target: ABCA7 (ATP-Binding Cassette, Sub-Family A (ABC1), Member 7 (ABCA7))

Bindungsspezifität: AA 130-180, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ABCA7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Spezifität: ABCA7 antibody is predicted to not cross-react with other ABC1 subfamily proteins.

Aufreinigung: ABCA7 Antibody is affinity chromatography purified via peptide column.

Immunogen: ABCA7 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human ABCA7. The immunogen is located within amino acids 130 - 180 of ABCA7.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ABCA7 antibody can be used for detection of ABCA7 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 5 μ,g/mL and immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 5 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: ABCA7 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: ABCA7 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu ABCA7

Target: ABCA7 (ATP-Binding Cassette, Sub-Family A (ABC1), Member 7 (ABCA7))

Andere Bezeichnung: ABCA7 (ABCA7 Produkte)

Synonyme: ABCX antikoerper, Abc51 antikoerper, ABCA-SSN antikoerper, ABCA7 antikoerper, ATP-binding cassette, sub-family A (ABC1), member 7 antikoerper, ATP binding cassette subfamily A member 7 antikoerper, ATP-binding cassette sub-family A member 7 antikoerper, Abca7 antikoerper, ABCA7 antikoerper, LOC100088822 antikoerper

Hintergrund: ABCA7 Antibody: ATP-binding cassette (ABC) transporters are an evolutionarily conserved family that use ATP hydrolysis to catalyze the transport of various molecules across cell membranes. They are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). ABCA7, a member of the ABC1 subfamily, is a full-size ABC transporter consisting of two sets of the multiple membrane-spanning domains plus the Walker motifs for the ATP interaction. ABCA7 shows the highest homology to ABCA1, an essential molecule for cholesterol homeostasis. The high expression levels of ABCA7 in peripheral leukocytes, thymus, spleen and bone marrow suggests a role in the immune system lipid homeostasis.

Molekulargewicht: Predicted: 236 kDa

Observed: 240 kDa

Gen-ID: 10347

NCBI Accession: NP_061985

UniProt: Q8IZY2