ABCA7 Antikörper (N-Term)

Produktnummer ABIN1449921

Der Kaninchen Polyklonal anti-ABCA7 Antikörper (ABIN1449921) detektiert spezifisch ABCA7 in WB, IF und EIA. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für ABCA7 Antikörper (N-Term) (ABIN1449921)

Target: ABCA7 (ATP-Binding Cassette, Sub-Family A (ABC1), Member 7 (ABCA7))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ABCA7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Produktdetails anti-ABCA7 Antikörper

Bindungsspezifität: N-Term

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 18 amino acid synthetic peptide near the amino terminus of Human ABCA7

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu ABCA7

Target: ABCA7 (ATP-Binding Cassette, Sub-Family A (ABC1), Member 7 (ABCA7))

Andere Bezeichnung: ABCA7

Hintergrund: ATP-binding cassette (ABC) transporters are an evolutionarily conserved family that use ATP hydrolysis to catalyze the transport of various molecules across cell membranes. They are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). ABCA7, a member of the ABC1 subfamily, is a full-size ABC transporter consisting of two sets of the multiple membrane-spanning domains plus the Walker motifs for the ATP interaction. ABCA7 shows the highest homology to ABCA1, an essential molecule for cholesterol homeostasis. The high expression levels of ABCA7 in peripheral leukocytes, thymus, spleen and bone marrow suggests a role in the immune system lipid homeostasis.Synonyms: ABCA-SSN, ATP-binding cassette sub-family A member 7, Autoantigen SS-N, Macrophage ABC transporter

Gen-ID: 10347

NCBI Accession: NP_061985