LRRFIP2 Antikörper (C-Term)

Produktnummer ABIN6991500

Produktdetails anti-LRRFIP2 Antikörper

Target: LRRFIP2 (Leucine Rich Repeat (In FLII) Interacting Protein 2 (LRRFIP2))

Bindungsspezifität: AA 620-670, C-Term

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LRRFIP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Spezifität: Three isoforms of LRRFIP2 are known to exist, this antibody will recognize all three. LRRFIP2 antibody is predicted to not cross-react with other LRRFIP family members.

Aufreinigung: LRRFIP2 Antibody is affinity chromatography purified via peptide column.

Immunogen: LRRFIP2 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human LRRFIP2. The immunogen is located within amino acids 620 - 670 of LRRFIP2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: LRRFIP2 antibody can be used for detection of LRRFIP2 by Western blot at 0.5 and 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in rat samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: LRRFIP2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: LRRFIP2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu LRRFIP2

Target: LRRFIP2 (Leucine Rich Repeat (In FLII) Interacting Protein 2 (LRRFIP2))

Andere Bezeichnung: LRRFIP2 (LRRFIP2 Produkte)

Synonyme: HUFI-2 antikoerper, 5133400F20Rik antikoerper, AI850587 antikoerper, wu:fj34c02 antikoerper, zgc:113956 antikoerper, zgc:63771 antikoerper, LRR binding FLII interacting protein 2 antikoerper, leucine rich repeat (in FLII) interacting protein 2 antikoerper, leucine rich repeat (in FLII) interacting protein 2 L homeolog antikoerper, LRRFIP2 antikoerper, Lrrfip2 antikoerper, lrrfip2 antikoerper, lrrfip2.L antikoerper

Hintergrund: LRRFIP2 Antibody: The leucine-rich repeat FLI-I-interacting protein 2 (LRRFIP2), like the related protein LRRFIP1, was identified in a yeast two-hybrid system through binding to the LRR domain of human FLI. It can activate the Wnt signaling pathway in cultured cells and is thought to be a component of the Wnt signaling pathway that modulates Wnt signaling through interactions with Disheveled to increase the cellular levels and transcription activity of beta-catenin. LRRFIP2 has recently been characterized as a positive regulator of the TLR4 signaling pathway for activating NF-κ,B during the early host response to LPS stimulation through binding to the TLR adaptor protein MyD88, and that this interaction with MyD88 is governed by phosphorylation of specific residues in LRRFIP2.

Gen-ID: 9209

NCBI Accession: NP_006300

UniProt: Q9Y608