LRRFIP2 Antikörper (AA 150-340)
Kurzübersicht für LRRFIP2 Antikörper (AA 150-340) (ABIN7268214)
Target
Alle LRRFIP2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 150-340
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Verwendungszweck
- LRRFIP2 Rabbit pAb
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Sequenz
- VIEEQEEQMA EFYRENEEKS KELERQKHMC SVLQHKMEEL KEGLRQRDEL IEKHGLVIIP DGTPNGDVSH EPVAGAITVV SQEAAQVLES AGEGPLDVRL RKLAGEKEEL LSQIRKLKLQ LEEERQKCSR NDGTVGDLAG LQNGSDLQFI EMQRDANRQI SEYKFKLSKA EQDITTLEQS ISRLEGQVLR Y
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 150-340 of human LRRFIP2 (NP_060194.1).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000,IF,1:50 - 1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- LRRFIP2 (Leucine Rich Repeat (In FLII) Interacting Protein 2 (LRRFIP2))
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Andere Bezeichnung
- LRRFIP2
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Hintergrund
- The protein encoded by this gene, along with MYD88, binds to the cytosolic tail of toll-like receptor 4 (TLR4), which results in activation of nuclear factor kappa B signaling. The ubiquitin-like protein FAT10 prevents the interaction of the encoded protein and TLR4, thereby inactivating the nuclear factor kappa B signaling pathway. In addition, this protein can downregulate the NLRP3 inflammasome by recruiting the caspase-1 inhibitor Flightless-I to the inflammasome complex.,LRRFIP2,HUFI-2,Epigenetics & Nuclear Signaling,Signal Transduction,Immunology & Inflammation,Toll-like Receptor Signaling Pathway,Cell Intrinsic Innate Immunity Signaling Pathway,TLR Signaling,Stem Cells,LRRFIP2
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Gen-ID
- 9209
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UniProt
- Q9Y608
Target
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