NALP8 Antikörper (N-Term)

Produktnummer ABIN6991405

Produktdetails anti-NALP8 Antikörper

Target: NALP8 (NLRP8) (NLR Family, Pyrin Domain Containing 8 (NLRP8))

Bindungsspezifität: AA 130-180, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NALP8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: NALP8 Antibody is affinity chromatography purified via peptide column.

Immunogen: NALP8 antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human NALP8. The immunogen is located within amino acids 130 - 180 of NALP8.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: NALP8 antibody can be used for detection of NALP8 by Western blot at 1 μ,g/mL.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: NALP8 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: NALP8 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu NALP8

Target: NALP8 (NLRP8) (NLR Family, Pyrin Domain Containing 8 (NLRP8))

Andere Bezeichnung: NALP8 (NLRP8 Produkte)

Synonyme: CLR19.2 antikoerper, NALP8 antikoerper, NOD16 antikoerper, PAN4 antikoerper, NLR family pyrin domain containing 8 antikoerper, NLRP8 antikoerper

Hintergrund: NALP8 Antibody: NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP8 has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. It maps to chromosome 19q13.42 and is thought to be expressed in testis and ovary, suggesting that NALP8 may be involved in reproduction. Surprisingly, NALP8 seems to be universal in mammals except for rodents, suggesting that the gene may have been lost during evolution.

Gen-ID: 126205

NCBI Accession: NP_789781

UniProt: Q86W28

Pathways: Inflammasome