WNT10A Antikörper (C-Term)

Produktnummer ABIN6990921

Produktdetails anti-WNT10A Antikörper

Target: WNT10A (Wingless-Type MMTV Integration Site Family, Member 10A (WNT10A))

Bindungsspezifität: AA 300-350, C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser WNT10A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Spezifität: This Wnt10a antibody is predicted to not cross-react with Wnt10b.

Aufreinigung: Wnt10a Antibody is affinity chromatography purified via peptide column.

Immunogen: Wnt10a antibody was raised against a 14 amino acid synthetic peptide from near the carboxy terminus of human Wnt10a. The immunogen is located within amino acids 300 - 350 of Wnt10a.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Wnt10a antibody can be used for detection of Wnt10a by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human and mouse samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Wnt10a Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: Wnt10a antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu WNT10A

Target: WNT10A (Wingless-Type MMTV Integration Site Family, Member 10A (WNT10A))

Andere Bezeichnung: Wnt10a (WNT10A Produkte)

Synonyme: WNT10A antikoerper, wnt10a/12 antikoerper, wnt10a antikoerper, OODD antikoerper, SSPS antikoerper, STHAG4 antikoerper, WNT-10A antikoerper, Wnt family member 10A antikoerper, protein Wnt-10a antikoerper, Wnt10a protein antikoerper, hypothetical protein antikoerper, WNT10A protein antikoerper, Wnt family member 10A L homeolog antikoerper, wingless-type MMTV integration site family, member 10A antikoerper, wingless-type MMTV integration site family, member 10a antikoerper, WNT10A antikoerper, LOC778792 antikoerper, CpipJ_CPIJ005839 antikoerper, Wnt10a antikoerper, wnt10a antikoerper, wnt10a.L antikoerper

Hintergrund: Wnt10a Antibody: Wnt10a is a member of the Wnt family, a gene family that encodes secreted signaling proteins that play crucial roles in normal development such as regulation of cell fate and patterning during embryogenesis as well as neoplastic transformation. Elevated levels of Wnt10a have been detected in several human tumors and cancer cell lines including colorectal cancer and chronic lymphocytic leukemia and it has been suggested that uncontrolled Wnt signaling may contribute to the defect in apoptosis that characterizes these malignancies. Recently, a mutation in Wnt10a was found to be associated with odonto-onycho-dermal dysplasia, an autosomal recessive ectodermal dysplasia.

Molekulargewicht: Predicted: 46 kDa

Observed: 46 kDa

Gen-ID: 80326

UniProt: Q9GZT5

Pathways: WNT Signalweg