WNT10B Antikörper (AA 130-180)

Produktnummer ABIN6990912

Produktdetails anti-WNT10B Antikörper

Target: WNT10B (Wingless-Type MMTV Integration Site Family, Member 10B (WNT10B))

Bindungsspezifität: AA 130-180

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser WNT10B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: Two isoforms of Wnt10b are known to exist, this antibody will only recognize the longer isoform. This Wnt10b antibody will not cross-react with Wnt10a.

Aufreinigung: Wnt10b Antibody is affinity chromatography purified via peptide column.

Immunogen: Wnt10b antibody was raised against a 15 amino acid synthetic peptide from near the center of human Wnt10b. The immunogen is located within amino acids 130 - 180 of Wnt10b.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Wnt10b antibody can be used for detection of Wnt10b by Western blot at 2 - 4 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunohistochemistry in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Wnt10b Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: Wnt10b antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu WNT10B

Target: WNT10B (Wingless-Type MMTV Integration Site Family, Member 10B (WNT10B))

Andere Bezeichnung: Wnt10b (WNT10B Produkte)

Synonyme: WNT10B antikoerper, Xwnt-10b antikoerper, Xwnt10b antikoerper, wnt-12 antikoerper, Wnt12 antikoerper, SHFM6 antikoerper, WNT-12 antikoerper, Xwnt-10 antikoerper, wnt10 antikoerper, wnt10-A antikoerper, Zwnt[d] antikoerper, wnt10br antikoerper, wnt[d] antikoerper, Wnt family member 10B antikoerper, wingless-type MMTV integration site family, member 10B antikoerper, Wnt family member 10B S homeolog antikoerper, wingless-type MMTV integration site family, member 10b antikoerper, WNT10B antikoerper, wnt10b antikoerper, Wnt10b antikoerper, wnt10b.S antikoerper

Hintergrund: Wnt10b Antibody: Wnt10b is a member of the Wnt family, a gene family that encodes secreted signaling proteins that play crucial roles in normal development such as regulation of cell fate and patterning during embryogenesis as well as neoplastic transformation. Wnt10b is found in the mouse mammary tumor virus insertion site where it is activated and causes mammary tumors. Elevated levels of Wnt10b have also been detected in human breast carcinomas. Wnt10b is known to be involved in adipogenesis, maintaining the preadipocyte in an undifferentiated state. More recently, Wnt10b has been shown to promote epithelial cell differentiation and hair shaft growth, demonstrating that Wnt10b has multiple roles in cell growth and differentiation.

Molekulargewicht: Predicted: 43 kDa

Observed: 47 kDa

Gen-ID: 7480

NCBI Accession: NP_003385

UniProt: O00744

Pathways: WNT Signalweg, Skeletal Muscle Fiber Development