FEZ1 Antikörper (C-Term)

Produktnummer ABIN6990766

Produktdetails anti-FEZ1 Antikörper

Target: FEZ1 (Fasciculation and Elongation Protein zeta 1 (Zygin I) (FEZ1))

Bindungsspezifität: AA 270-320, C-Term

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FEZ1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: FEZ1 Antibody is affinity chromatography purified via peptide column.

Immunogen: FEZ1 antibody was raised against a 19 amino acid synthetic peptide from near the carboxy terminus of human FEZ1. The immunogen is located within amino acids 270 - 320 of FEZ1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: FEZ1 antibody can be used for the detection of FEZ1 by Western blot at 0.5 - 1 μ,g/mL. Despite its predicted molecular weight, FEZ1 will often run at higher molecular weight in SDS-PAGE.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: FEZ1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: FEZ1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu FEZ1

Target: FEZ1 (Fasciculation and Elongation Protein zeta 1 (Zygin I) (FEZ1))

Andere Bezeichnung: FEZ1 (FEZ1 Produkte)

Synonyme: UNC-76 antikoerper, UNC76 antikoerper, wu:fj14c12 antikoerper, zgc:73258 antikoerper, fez1 antikoerper, xfez1 antikoerper, fasciculation and elongation protein zeta 1 antikoerper, fasciculation and elongation protein zeta 1 (zygin I) antikoerper, fasciculation and elongation protein zeta 1 L homeolog antikoerper, FEZ1 antikoerper, Fez1 antikoerper, fez1 antikoerper, fez1.L antikoerper

Hintergrund: FEZ1 Antibody: Similar to its C. elegans homolog UNC-76, mammalian FEZ1, an abundant membrane protein and protein kinase C (PKC)-Z substrate, is involved in axonal guidance. Following phosphorylation by PKC-Z, FEZ1 translocates from the plasma membrane to the cytoplasm. FEZ1 is then able to interact with a number of proteins involved in axonal outgrowth and cellular transport such as DISC1, a candidate gene for schizophrenia, as well as kinesin-1, a microtubule-based motor protein. FEZ1 also interacts with proteins involved in transcriptional regulation and chromatin remodeling, suggesting that FEZ1 may have nuclear regulatory functions in addition to those for neuronal development. At least two distinct isoforms of FEZ1 are known to exist.

Molekulargewicht: Predicted: 42 kDa

Observed: 46 kDa

Gen-ID: 9638

UniProt: Q99689