Neurotrypsin Antikörper (N-Term)

Produktnummer ABIN6990739

Produktdetails anti-Neurotrypsin Antikörper

Target: Neurotrypsin (PRSS12) (Protease, serine, 12 (Neurotrypsin, Motopsin) (PRSS12))

Bindungsspezifität: AA 110-160, N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Neurotrypsin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Aufreinigung: Neurotrypsin Antibody is affinity chromatography purified via peptide column.

Immunogen: Neurotrypsin antibody was raised against a 23 amino acid synthetic peptide from near the amino terminus of human neurotrypsin. The immunogen is located within amino acids 110 - 160 of Neurotrypsin.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Neurotrypsin antibody can be used for detection of neurotrypsin by Western blot at 0.5 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Neurotrypsin Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: Neurotrypsin antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu Neurotrypsin

Target: Neurotrypsin (PRSS12) (Protease, serine, 12 (Neurotrypsin, Motopsin) (PRSS12))

Andere Bezeichnung: Neurotrypsin (PRSS12 Produkte)

Synonyme: PRSS12 antikoerper, BSSP-3 antikoerper, BSSP3 antikoerper, MRT1 antikoerper, Bssp-3 antikoerper, motopsin antikoerper, Nt antikoerper, protease, serine 12 antikoerper, 26S proteasome regulatory SU antikoerper, prsS12 antikoerper, neurotrypsin antikoerper, protease, serine 12 neurotrypsin (motopsin) antikoerper, PRSS12 antikoerper, prsS12 antikoerper, HAN_3g451 antikoerper, CpipJ_CPIJ005457 antikoerper, CpipJ_CPIJ005852 antikoerper, Prss12 antikoerper

Hintergrund: Neurotrypsin Antibody: Neurotrypsin is a central nervous system-expressed serine protease whose truncation or absence causes nonsyndromic mental retardation. It is most prominently expressed in structures that are involved in the processing and storage of learned behavior and memory, such as the cerebral cortex, the hippocampus, and amygdala. Evidence suggests that neurotrypsin has multiple functions, including axonal outgrowth, maintaining neuronal plasticity, and arranging the perineuronal environment, partly in coordination with other proteases including tissue plasminogen activator. At least two isoforms of neurotrypsin are known to exist.

Molekulargewicht: Predicted: 96 kDa

Observed: 96 kDa

Gen-ID: 8492

UniProt: P56730