Neurotrypsin Antikörper (N-Term)
Kurzübersicht für Neurotrypsin Antikörper (N-Term) (ABIN500334)
Target
Alle Neurotrypsin (PRSS12) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Spezifität
- This antibody detects Neurotrypsin at N-term.
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Kreuzreaktivität (Details)
- Species reactivity (tested):Human, mouse, rat
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Aufreinigung
- Peptide affinity chromatography
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Immunogen
- Neurotrypsin antibody was raised against a 23 amino acid peptide from near the amino terminus of human neurotrypsin.
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Isotyp
- IgG
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Applikationshinweise
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ELISA. Western blot: 0.5 - 1 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Buffer
- PBS containing 0.02 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- Neurotrypsin (PRSS12) (Protease, serine, 12 (Neurotrypsin, Motopsin) (PRSS12))
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Andere Bezeichnung
- Neurotrypsin
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Hintergrund
- Neurotrypsin is a central nervous system-expressed serine protease whose truncation or absence causes nonsyndromic mental retardation. It is most prominently expressed in structures that are involved in the processing and storage of learned behavior and memory, such as the cerebral cortex, the hippocampus, and amygdala. Evidence suggests that neurotrypsin has multiple functions, including axonal outgrowth, maintaining neuronal plasticity, and arranging the perineuronal environment, partly in coordination with other proteases including tissue plasminogen activator. At least two isoforms of neurotrypsin are known to exist.Synonyms: Leydin, Motopsin, PRSS12, Serine protease 12
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Gen-ID
- 8492
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UniProt
- P56730
Target
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