C1QTNF3 Antikörper (AA 90-140)

Produktnummer ABIN6990596

Produktdetails anti-C1QTNF3 Antikörper

Target: C1QTNF3 (C1q and Tumor Necrosis Factor Related Protein 3 (C1QTNF3))

Bindungsspezifität: AA 90-140

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser C1QTNF3 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: Multiple isoforms of CTRP3 are known to exist. CTRP3 antibody is predicted to not recognize other members of the CTRP protein family.

Aufreinigung: CTRP3 Antibody is affinity chromatography purified via peptide column.

Immunogen: Anti-CTRP3 antibody was raised against a peptide corresponding to 16 amino acids near the center of human CTRP3. The immunogen is located within amino acids 90-140 of CTRP3.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1 μ,g/mL, IHC: 2 μ,g/mL, IF: 10 μ,g/mL.

Antibody validated: Western Blot in human, mouse and rat samples, Immunohistochemistry in mouse samples, Immunofluorescence in mouse samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: CTRP3 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: CTRP3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu C1QTNF3

Target: C1QTNF3 (C1q and Tumor Necrosis Factor Related Protein 3 (C1QTNF3))

Andere Bezeichnung: CTRP3 (C1QTNF3 Produkte)

Synonyme: Amacr antikoerper, zgc:110704 antikoerper, C1ATNF3 antikoerper, CORCS antikoerper, CORS antikoerper, CORS-26 antikoerper, CORS26 antikoerper, CTRP3 antikoerper, 2310005P21Rik antikoerper, Corcs antikoerper, Cors antikoerper, C1q and tumor necrosis factor related protein 3 antikoerper, alpha-methylacyl-CoA racemase antikoerper, C1q and TNF related 3 antikoerper, C1QTNF3 antikoerper, amacr antikoerper, C1qtnf3 antikoerper

Hintergrund: CTRP3 Antibody: Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines. One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-alpha-related proteins (CTRPs) 1-7. Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene. It has been suggested that CTRP3 may play a role in skeletal development.

Molekulargewicht: Predicted: 27kD

Observed: 30 kD (Post-modyfication: 1 N-linked glycosylation) kDa

Gen-ID: 114899

NCBI Accession: NP_852100

UniProt: Q9BXJ4