C1QTNF3
Reaktivität: Human
ELISA, WB
Wirt: Kaninchen
Polyclonal
HRP
Applikationshinweise
ELISA. Western Blot: CTRP3 antibody can be used for the detection of CTRP3 by Western blot at 1 -2 μg/mL. Mouse heart cell lysate can be used as positive control. These proteins are oftenhighly modified post-translationally and migrate in SDS-PAGE at positions other than theirpredicted size. Immunohistochemistry. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Buffer
PBS containing 0.02 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C
Informationen zur Lagerung
Store the antibody undiluted at 2-8 °C.
Target
C1QTNF3
(C1q and Tumor Necrosis Factor Related Protein 3 (C1QTNF3))
Amacr antikoerper, zgc:110704 antikoerper, C1ATNF3 antikoerper, CORCS antikoerper, CORS antikoerper, CORS-26 antikoerper, CORS26 antikoerper, CTRP3 antikoerper, 2310005P21Rik antikoerper, Corcs antikoerper, Cors antikoerper, C1q and tumor necrosis factor related protein 3 antikoerper, alpha-methylacyl-CoA racemase antikoerper, C1q and TNF related 3 antikoerper, C1QTNF3 antikoerper, amacr antikoerper, C1qtnf3 antikoerper
Hintergrund
Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines (reviewed in 1). One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-related proteins (CTRPs) 1-7 (2). Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues (3). An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene (4). Multiple isoforms of human CTRP3 have been reported. It has been suggested that CTRP3 may play a role in skeletal development (5).Synonyms: C1ATNF3, CORS26, CTRP3, Complement C1q tumor necrosis factor-related protein 3, Secretory protein CORS26