TNFRSF6B Antikörper (N-Term)

Produktnummer ABIN6990301

Produktdetails anti-TNFRSF6B Antikörper

Target: TNFRSF6B (Tumor Necrosis Factor Receptor Superfamily, Member 6b, Decoy (TNFRSF6B))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TNFRSF6B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: DcR3 Antibody is Ion exchange chromatography purified.

Immunogen: DcR3 antibody was raised against a peptide corresponding to amino acids near the amino terminus of human DcR3 precursor. The immunogen is located within the first 50 amino acids of DcR3.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: DcR3 antibody can be used for detection of DcR3 expression by Western blot 0.5 μ,g/mL. An approximately 33 kDa band can be detected. Antibody can also be used for immunohistochemistry starting at 1 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunohistochemistry in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: DcR3 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: DcR3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu TNFRSF6B

Target: TNFRSF6B (Tumor Necrosis Factor Receptor Superfamily, Member 6b, Decoy (TNFRSF6B))

Andere Bezeichnung: DcR3 (TNFRSF6B Produkte)

Synonyme: DCR3 antikoerper, DJ583P15.1.1 antikoerper, M68 antikoerper, M68E antikoerper, TR6 antikoerper, dcr3 antikoerper, m68 antikoerper, tr6 antikoerper, TNF receptor superfamily member 6b antikoerper, tumor necrosis factor receptor superfamily, member 11b antikoerper, regulator of telomere elongation helicase 1 antikoerper, TNF receptor superfamily member 6b L homeolog antikoerper, TNFRSF6B antikoerper, tnfrsf11b antikoerper, RTEL1 antikoerper, tnfrsf6b antikoerper, tnfrsf6b.L antikoerper

Hintergrund: DcR3 Antibody: Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors. Several novel members in the TNFR family including DR3, DR4, DR5, and DR6 were recently discovered and function as cell death receptors. Two decoy receptors, DcR1 and DcR2, were recently identified to compete with DR4 and DR5 for their ligand TRAIL binding. A novel decoy receptor was more recently discovered and designated DcR3 and TR6, respectively,. Unlike DcR1 and DcR2, DcR3 is a soluble rather than a membrane associated molecule. DcR3 binds to FasL and LIGHT and inhibits FasL and LIGHT induced apoptosis. DcR3 transcript is expressed in a number of lung and colon carcinomas and in some normal tissues.

Molekulargewicht: 33 kDa

Gen-ID: 8771

UniProt: O95407