ACE2 Antikörper

Produktnummer ABIN6989947

Produktdetails anti-ACE2 Antikörper

Target: ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))

Reaktivität: Human, Maus, Ratte, Hamster

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser ACE2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunofluorescence (Cultured Cells) (IF (cc))

Kreuzreaktivität: Hamster, Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: Synthetic Peptide within Human ACE2 aa 200-230.

Klon: 3B5

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IF(ICC) 1:50-200
IP(1-2 μg)
IHC()

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu ACE2

Target: ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))

Andere Bezeichnung: ACE2 (ACE2 Produkte)

Synonyme: ACE1 antikoerper, CD143 antikoerper, DCP antikoerper, DCP1 antikoerper, ICH antikoerper, MVCD3 antikoerper, ACEH antikoerper, 2010305L05Rik antikoerper, zgc:92514 antikoerper, angiotensin I converting enzyme antikoerper, angiotensin I converting enzyme 2 antikoerper, angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 antikoerper, ACE antikoerper, ACE2 antikoerper, Ace2 antikoerper, ace2 antikoerper

Hintergrund:

Synonyms: ACE 2 antibody, ACE related carboxypeptidase antibody, ACE-related carboxypeptidase antibody, ACE2 antibody, ACE2_HUMAN antibody, ACEH antibody, Angiotensin converting enzyme 2 antibody, Angiotensin converting enzyme homolog antibody, Angiotensin converting enzyme like protein antibody, Angiotensin I Converting Enzyme (peptidyl dipeptidase A) 2 antibody, Angiotensin I converting enzyme 2 antibody, Angiotensin-converting enzyme homolog antibody, DKFZP434A014 antibody, EC 3.4.17 antibody, metalloprotease MPROT 15 antibody, Metalloprotease MPROT15 antibody, OTTHUMP00000022963 antibody, Processed angiotensin-converting enzyme 2 antibody

Background: Angiotensin converting enzyme 2 (ACE2) is an exopeptidase that catalyses the conversion of angiotensin I to the nonapeptide angiotensin[1-9], or the conversion of angiotensin II to angiotensin 1-7. ACE2 has direct effects on cardiac function,a and is expressed predominantly in vascular endothelial cells of the heart and the kidneys. ACE2 is not sensitive to the ACE inhibitor drugs used to treat hypertension. ACE2 receptors have been shown to be the entry point into human cells for some coronaviruses, including the SARS virus[10]. A number of studies have identified that the entry point is the same for SARS-CoV-2, the COVID-19 virus.

Gen-ID: 59272

UniProt: Q9BYF1

Pathways: ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour