Ki-67 Antikörper (AA 2901-3000) (Cy3)
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- Target Alle Ki-67 (MKI67) Antikörper anzeigen
- Ki-67 (MKI67) (Antigen Identified By Monoclonal Antibody Ki-67 (MKI67))
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Bindungsspezifität
- AA 2901-3000
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Ki-67 Antikörper ist konjugiert mit Cy3
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Applikation
- Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc))
- Kreuzreaktivität
- Human, Maus
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human Ki-67
- Isotyp
- IgG
- Top Product
- Discover our top product MKI67 Primärantikörper
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- Applikationshinweise
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FCM 1:20-100
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- Ki-67 (MKI67) (Antigen Identified By Monoclonal Antibody Ki-67 (MKI67))
- Andere Bezeichnung
- Ki-67 (MKI67 Produkte)
- Synonyme
- MKI67 antikoerper, kia antikoerper, mki67 antikoerper, MGC132156 antikoerper, D630048A14Rik antikoerper, Ki-67 antikoerper, Ki67 antikoerper, KIA antikoerper, MIB-1 antikoerper, marker of proliferation Ki-67 antikoerper, marker of proliferation Ki-67 L homeolog antikoerper, marker of proliferation Ki-67 S homeolog antikoerper, antigen identified by monoclonal antibody Ki 67 antikoerper, antigen identified by monoclonal antibody Ki-67 antikoerper, nucleolar protein interacting with the FHA domain of MKI67 antikoerper, MKI67 antikoerper, mki67 antikoerper, mki67.L antikoerper, mki67.S antikoerper, Mki67 antikoerper, NIFK antikoerper
- Hintergrund
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Synonyms: Proliferation marker protein Ki-67, MKI67, Antigen identified by monoclonal antibody Ki-67, Antigen KI67
Background: Required to maintain individual mitotic chromosomes dispersed in the cytoplasm following nuclear envelope disassembly (PubMed:27362226). Associates with the surface of the mitotic chromosome, the perichromosomal layer, and covers a substantial fraction of the chromosome surface (PubMed:27362226). Prevents chromosomes from collapsing into a single chromatin mass by forming a steric and electrostatic charge barrier: the protein has a high net electrical charge and acts as a surfactant, dispersing chromosomes and enabling independent chromosome motility (PubMed:27362226). Binds DNA, with a preference for supercoiled DNA and AT-rich DNA (PubMed:10878551). Does not contribute to the internal structure of mitotic chromosomes (By similarity). May play a role in chromatin organization (PubMed:24867636). It is however unclear whether it plays a direct role in chromatin organization or whether it is an indirect consequence of its function in maintaining mitotic chromosomes dispersed (Probable).
- Gen-ID
- 4288
- UniProt
- P46013
- Pathways
- Glycosaminoglycan Metabolic Process
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