YWHAB/YWHAZ Antikörper (pSer184, pSer186) (Alexa Fluor 647)

Produktnummer ABIN6979862

Produktdetails anti-YWHAB/YWHAZ Antikörper (Alexa Fluor 647)

Target: YWHAB/YWHAZ (14-3-3 beta/zeta (YWHAB/YWHAZ))

Bindungsspezifität: pSer184, pSer186

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser YWHAB/YWHAZ Antikörper ist konjugiert mit Alexa Fluor 647

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Dog,Cow,Pig,Horse,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthesised phosphopeptide derived from human 14-3-3 beta + zeta around the phosphorylation site of Ser186 / Ser184

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu YWHAB/YWHAZ

Target: YWHAB/YWHAZ (14-3-3 beta/zeta (YWHAB/YWHAZ))

Andere Bezeichnung: 14-3-3 beta + zeta (YWHAB/YWHAZ Produkte)

Synonyme: 14-3-3z antikoerper, 14-3-3zeta antikoerper, kcip-1 antikoerper, ywhaq antikoerper, Ywhaz antikoerper, ACYPI003154 antikoerper, 1433z antikoerper, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta antikoerper, 14-3-3 protein zeta antikoerper, ywhaz antikoerper, 14-3-3zeta antikoerper, YWHAZ antikoerper, 1433z antikoerper

Hintergrund:

Synonyms: 14-3-3 beta + zeta (phospho S184 + S186), 14-3-3 beta + zeta (phospho S186), 14-3-3 beta + zeta (phospho Ser186), p-14-3-3 beta + zeta (Ser186) 14 3 3 protein beta, 14 3 3 protein beta/alpha, 14 3 3 protein zeta/delta, 14 3 3 zeta, HS1, KCIP1, YWHAB, YWHAZ.

Background: Members of the 14-3-3 family of proteins are highly conserved proteins, localized in neurons, and are axonally transported to the nerve terminals. They are also present, at lower levels, in various other eukaryotic tissues. 14-3-3 proteins appear to play important roles in a variety of signal transduction pathways, including those involved in cell cycle regulation and cell survival. Because 14-3-3 proteins bind to specific phosphoserine-containing sequences they are likely to have an important role in signaling pathways mediated by serine/threonine protein kinases. Evidence indicates 14-3-3 is required for Raf 1 kinase activity and phosphorylation amoung many other functions.

Gen-ID: 7529

UniProt: P31946