YWHAB/YWHAZ Antikörper (pSer184, pSer186)

Produktnummer ABIN6287849

Produktdetails anti-YWHAB/YWHAZ Antikörper

Target: YWHAB/YWHAZ (14-3-3 beta/zeta (YWHAB/YWHAZ))

Bindungsspezifität: AA 120-200, pSer184, pSer186

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser YWHAB/YWHAZ Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Verwendungszweck: 14-3-3 β/ζ is a protein encoded by the YWHAZ gene which is approximately 27,7 kDa. 14-3-3 β/ζ is localised to the cytoplasm and melanosome. It is involved in the activation of cAMP-dependent PKA, development slit-robo signalling and activation of BH3-only proteins. It is an adapter protein implicated in the regulation of a large spectrum of both general and specialized signalling pathways. It binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. 14-3-3 β/ζ is expressed in the nervous system, intestine, skin, blood and eye. STJ90562 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This primary antibody specifically binds to endogenous 14-3-3 β/ζ protein which only binds about S184/186 when S184/186 is phosphorylated.

Spezifität: Phospho-14-3-3 β/ζ (S184/186) Polyclonal Antibody detects endogenous levels of 14-3-3 β/ζ protein only when phosphorylated at S184/186.

Produktmerkmale: Rabbit polyclonal to Phospho-14-3-3 β/ζ (S184/186).

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human 14-3-3 beta/zeta around the phosphorylation site of S184/186.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000
ELISA 1:5000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C, and avoid repeat freeze-thaw cycles.

Details zu YWHAB/YWHAZ

Target: YWHAB/YWHAZ (14-3-3 beta/zeta (YWHAB/YWHAZ))

Andere Bezeichnung: 14-3-3 beta/zeta (YWHAB/YWHAZ Produkte)

Synonyme: 14-3-3z antikoerper, 14-3-3zeta antikoerper, kcip-1 antikoerper, ywhaq antikoerper, Ywhaz antikoerper, ACYPI003154 antikoerper, 1433z antikoerper, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta antikoerper, 14-3-3 protein zeta antikoerper, ywhaz antikoerper, 14-3-3zeta antikoerper, YWHAZ antikoerper, 1433z antikoerper

Molekulargewicht: 28 kDa

Gen-ID: 7534

UniProt: P63104