CR1L Antikörper (AA 51-150) (Alexa Fluor 555)

Produktnummer ABIN6978238

Produktdetails anti-CR1L Antikörper (Alexa Fluor 555)

Target: CR1L (Complement Component (3b/4b) Receptor 1-Like (CR1L))

Bindungsspezifität: AA 51-150

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CR1L Antikörper ist konjugiert mit Alexa Fluor 555

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Maus

Homologie: Rat

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Crry

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu CR1L

Target: CR1L (Complement Component (3b/4b) Receptor 1-Like (CR1L))

Andere Bezeichnung: Crry (CR1L Produkte)

Synonyme: CREG antikoerper, Cr1 antikoerper, Crry antikoerper, Mcp antikoerper, mCRY antikoerper, complement C3b/C4b receptor 1 like antikoerper, complement component (3b/4b) receptor 1-like antikoerper, CR1L antikoerper, Cr1l antikoerper

Hintergrund:

Synonyms: Mcp, Crry, mCRY, Complement component receptor 1-like protein, Complement regulatory protein Crry, Protein p65, Cr1l, Cry

Background: Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. Also acts as a decay-accelerating factor, preventing the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade. Plays a crucial role in early embryonic development by maintaining fetomaternal tolerance. Also acts as a costimulatory factor for T-cells which favors IL-4 secretion.

Gen-ID: 12946

UniProt: Q64735

Pathways: Komplementsystem