TESPA1 Antikörper (AA 231-330) (Alexa Fluor 488)

Produktnummer ABIN6978027

Produktdetails anti-TESPA1 Antikörper (Alexa Fluor 488)

Target: TESPA1 (Thymocyte Expressed, Positive Selection Associated 1 (TESPA1))

Bindungsspezifität: AA 231-330

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TESPA1 Antikörper ist konjugiert mit Alexa Fluor 488

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Kreuzreaktivität: Human

Homologie: Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TESPA1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu TESPA1

Target: TESPA1 (Thymocyte Expressed, Positive Selection Associated 1 (TESPA1))

Andere Bezeichnung: TESPA1 (TESPA1 Produkte)

Synonyme: KIAA0748 antikoerper, thymocyte expressed, positive selection associated 1 antikoerper, TESPA1 antikoerper

Hintergrund:

Synonyms: Protein TESPA1, TESPA1, Thymocyte-expressed positive selection-associated protein 1, KIAA0748, HSPC257

Background: Required for the development and maturation of T-cells, its function being essential for the late stages of thymocyte development (By similarity). Plays a role in T-cell antigen receptor (TCR)-mediated activation of the ERK and NFAT signaling pathways, possibly by serving as a scaffolding protein that promotes the assembly of the LAT signalosome in thymocytes. May play a role in the regulation of inositol 1,4,5-trisphosphate receptor-mediated Ca2+ release and mitochondrial Ca2+ uptake via the mitochondria-associated endoplasmic reticulum membrane (MAM) compartment.

Gen-ID: 9840

UniProt: A2RU30