ERO1LB Antikörper (AA 1-100) (Alexa Fluor 350)

Produktnummer ABIN6976563

Produktdetails anti-ERO1LB Antikörper (Alexa Fluor 350)

Target: ERO1LB (ERO1-Like beta (ERO1LB))

Bindungsspezifität: AA 1-100

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ERO1LB Antikörper ist konjugiert mit Alexa Fluor 350

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Maus, Ratte

Homologie: Human,Pig,Rabbit,Guinea Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ERO1LB

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu ERO1LB

Target: ERO1LB (ERO1-Like beta (ERO1LB))

Andere Bezeichnung: ERO1LB (ERO1LB Produkte)

Synonyme: RGD1563548 antikoerper, 1300013B24Rik antikoerper, 1700065B09Rik antikoerper, AI447560 antikoerper, ero1-beta antikoerper, endoplasmic reticulum oxidoreductase 1 beta antikoerper, ERO1-like beta (S. cerevisiae) antikoerper, Ero1b antikoerper, ERO1B antikoerper, Ero1lb antikoerper

Hintergrund:

Synonyms: Endoplasmic oxidoreductin-1-like protein B, ERO1-L-beta, ERO1B, ERO1-like protein beta, Oxidoreductin-1-L-beta

Background: Oxidoreductase involved in disulfide bond formation in the endoplasmic reticulum. Efficiently reoxidizes P4HB/PDI, the enzyme catalyzing protein disulfide formation, in order to allow P4HB to sustain additional rounds of disulfide formation. Other protein disulfide isomerase family members can also be reoxidized, but at lower rates compared to P4HB, including PDIA2 (50 % of P4HB reoxidation rate), as well as PDIA3, PDIA4, PDIA6 and NXNDC12 (<10 %). Following P4HB reoxidation, passes its electrons to molecular oxygen via FAD, leading to the production of reactive oxygen species (ROS) in the cell. May be involved in oxidative proinsulin folding in pancreatic cells, hence may play a role in glucose homeostasis.

Gen-ID: 56605

UniProt: Q86YB8

Pathways: SARS-CoV-2 Protein Interaktom