PSMA1 Antikörper

Produktnummer ABIN6944689

Produktdetails anti-PSMA1 Antikörper

Target: PSMA1 (Proteasome Subunit alpha Type 1 (PSMA1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser PSMA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: Recombinant protein within human PSMA1 aa 1-200

Klon: 10A2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IF(IHC-P) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu PSMA1

Target: PSMA1 (Proteasome Subunit alpha Type 1 (PSMA1))

Andere Bezeichnung: PSMA1 (PSMA1 Produkte)

Synonyme: PSMA1 antikoerper, pros30 antikoerper, DDBDRAFT_0204226 antikoerper, DDBDRAFT_0214956 antikoerper, DDB_0204226 antikoerper, DDB_0214956 antikoerper, C2 antikoerper, HC2 antikoerper, Pros-30 antikoerper, alpha-type antikoerper, NU antikoerper, PROS30 antikoerper, CC2 antikoerper, zgc:92726 antikoerper, 143314_at antikoerper, Alpha-6 antikoerper, CG4904 antikoerper, Dmel\CG4904 antikoerper, PROS-35 antikoerper, PROS-Dm35 antikoerper, Pros-35 antikoerper, Pros-Dm35 antikoerper, Prosalpha6 antikoerper, alpha6 antikoerper, alpha_dm antikoerper, anon-SAGE:Wang-116 antikoerper, pros 35 antikoerper, pros35 antikoerper, proteasome subunit alpha 1 antikoerper, proteasome subunit alpha type 1 antikoerper, 20S proteasome subunit C2 antikoerper, proteasome (prosome, macropain) subunit, alpha type 1 antikoerper, proteasome subunit alpha 1 L homeolog antikoerper, Proteasome alpha6 subunit antikoerper, PSMA1 antikoerper, psma1 antikoerper, CNB05540 antikoerper, psmA1 antikoerper, Psma1 antikoerper, psma1.L antikoerper, Prosalpha6 antikoerper

Hintergrund:

Synonyms: Proteasome subunit alpha type-1, 30 kDa prosomal protein, Macropain subunit C2, Multicatalytic endopeptidase complex subunit C2, Proteasome component C2, Proteasome nu chain, PROS-30, PSMA1, HC2, NU, PROS30, PSC2.

Background: Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).

Gen-ID: 5682

UniProt: P25786

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA