PSMA1 Antikörper (C-Term)

Produktnummer ABIN6264468

Produktdetails anti-PSMA1 Antikörper

Target: PSMA1 (Proteasome Subunit alpha Type 1 (PSMA1))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PSMA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Spezifität: PSMA1 Antibody detects endogenous levels of total PSMA1.

Homologie: Bovine,Horse,Sheep,Rabbit,Chicken

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human PSMA1, corresponding to a region within C-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu PSMA1

Target: PSMA1 (Proteasome Subunit alpha Type 1 (PSMA1))

Andere Bezeichnung: PSMA1 (PSMA1 Produkte)

Synonyme: PSMA1 antikoerper, pros30 antikoerper, DDBDRAFT_0204226 antikoerper, DDBDRAFT_0214956 antikoerper, DDB_0204226 antikoerper, DDB_0214956 antikoerper, C2 antikoerper, HC2 antikoerper, Pros-30 antikoerper, alpha-type antikoerper, NU antikoerper, PROS30 antikoerper, CC2 antikoerper, zgc:92726 antikoerper, 143314_at antikoerper, Alpha-6 antikoerper, CG4904 antikoerper, Dmel\CG4904 antikoerper, PROS-35 antikoerper, PROS-Dm35 antikoerper, Pros-35 antikoerper, Pros-Dm35 antikoerper, Prosalpha6 antikoerper, alpha6 antikoerper, alpha_dm antikoerper, anon-SAGE:Wang-116 antikoerper, pros 35 antikoerper, pros35 antikoerper, proteasome subunit alpha 1 antikoerper, proteasome subunit alpha type 1 antikoerper, 20S proteasome subunit C2 antikoerper, proteasome (prosome, macropain) subunit, alpha type 1 antikoerper, proteasome subunit alpha 1 L homeolog antikoerper, Proteasome alpha6 subunit antikoerper, PSMA1 antikoerper, psma1 antikoerper, CNB05540 antikoerper, psmA1 antikoerper, Psma1 antikoerper, psma1.L antikoerper, Prosalpha6 antikoerper

Hintergrund:

Description: Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).

Gene: PSMA1

Molekulargewicht: 29kDa

Gen-ID: 5682

UniProt: P25786

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA