ARPC5 Antikörper

Produktnummer ABIN6944379

Produktdetails anti-ARPC5 Antikörper

Target: ARPC5 (Actin Related Protein 2/3 Complex, Subunit 5, 16kDa (ARPC5))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser ARPC5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: Recombinant human p16 ARC around N-terminus

Klon: 8D8

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IF(ICC) 1:50-200
IHC()

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu ARPC5

Target: ARPC5 (Actin Related Protein 2/3 Complex, Subunit 5, 16kDa (ARPC5))

Andere Bezeichnung: p16 ARC (ARPC5 Produkte)

Synonyme: arc16 antikoerper, p16-arc antikoerper, ARPC5 antikoerper, APOBEC4 antikoerper, ARC16 antikoerper, dJ127C7.3 antikoerper, p16-Arc antikoerper, MGC86407 antikoerper, 5830443F10Rik antikoerper, arpc5 antikoerper, fb09c07 antikoerper, fb12b05 antikoerper, fc56c07 antikoerper, wu:fb09c07 antikoerper, wu:fb12b05 antikoerper, wu:fc56c07 antikoerper, actin related protein 2/3 complex subunit 5 antikoerper, actin related protein 2/3 complex subunit 5 L homeolog antikoerper, actin related protein 2/3 complex, subunit 5 antikoerper, actin related protein 2/3 complex, subunit 5B antikoerper, actin related protein 2/3 complex, subunit 5A antikoerper, ARPC5 antikoerper, arpc5 antikoerper, arpc5.L antikoerper, Arpc5 antikoerper, arpc5b antikoerper, arpc5a antikoerper

Hintergrund:

Synonyms: Actin-related protein 2/3 complex subunit 5, Arp2/3 complex 16 kDa subunit, p16-ARC, ARPC5

Background: Component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF) (PubMed:9230079). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility (PubMed:9230079). In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA (PubMed:29925947). The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs).

Gen-ID: 10092

UniProt: O15511

Pathways: RTK Signalweg, Regulation of Actin Filament Polymerization