NDUFS3 Antikörper

Produktnummer ABIN6944233

Produktdetails anti-NDUFS3 Antikörper

Target: NDUFS3 (NADH Dehydrogenase (Ubiquinone) Fe-S Protein 3, 30kDa (NADH-Coenzyme Q Reductase) (NDUFS3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser NDUFS3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human

Aufreinigung: Purified by Protein A.

Immunogen: Recombinant protein within human NDUFS3 aa 100 to the C-terminus

Klon: 9B7

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu NDUFS3

Target: NDUFS3 (NADH Dehydrogenase (Ubiquinone) Fe-S Protein 3, 30kDa (NADH-Coenzyme Q Reductase) (NDUFS3))

Andere Bezeichnung: NDUFS3 (NDUFS3 Produkte)

Synonyme: CI-30 antikoerper, 0610010M09Rik antikoerper, CI-30kD antikoerper, GB15355 antikoerper, zgc:112520 antikoerper, NADH:ubiquinone oxidoreductase core subunit S3 antikoerper, NADH dehydrogenase (ubiquinone) Fe-S protein 3 antikoerper, NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial antikoerper, NADH:ubiquinone oxidoreductase core subunit S3 S homeolog antikoerper, NADH dehydrogenase (ubiquinone) Fe-S protein 3, (NADH-coenzyme Q reductase) antikoerper, NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) antikoerper, NDUFS3 antikoerper, Ndufs3 antikoerper, ndufs3 antikoerper, LOC411411 antikoerper, ndufs3.S antikoerper, LOC100228726 antikoerper

Hintergrund:

Synonyms: NADH dehydrogenase [ubiquinone] iron-sulfur protein 3 mitochondrial, Complex I-30kD, NADH-ubiquinone oxidoreductase 30 kDa subunit, CI-30kD, NDUFS3, MC1DN8, NADH:ubiquinone oxidoreductase core subunit S3.

Background: This gene encodes one of the iron-sulfur protein (IP) components of mitochondrial NADH:ubiquinone oxidoreductase (complex I). Mutations in this gene are associated with Leigh syndrome resulting from mitochondrial complex I deficiency. NDUFS3 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.

Gen-ID: 4722

UniProt: O75489

Pathways: Negative Regulation of intrinsic apoptotic Signaling