NDUFS3 Antikörper (Center)

Produktnummer ABIN2856200

Produktdetails anti-NDUFS3 Antikörper

Target: NDUFS3 (NADH Dehydrogenase (Ubiquinone) Fe-S Protein 3, 30kDa (NADH-Coenzyme Q Reductase) (NDUFS3))

Bindungsspezifität: Center

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NDUFS3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunocytochemistry (ICC)

Produktmerkmale: Rabbit Polyclonal antibody to NDUFS3 (NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30 kDa (NADH-coenzyme Q reductase))
NDUFS3 antibody

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human NDUFS3. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*

Kommentare:

Positive Control: Jurkat , Raji , NCI-H929

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1XPBS, 20 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Referenzen für anti-NDUFS3 Antikörper (ABIN2856200)

Qiao, Jin, Pang, Moskophidis, Mivechi: "The transcriptional regulator of the chaperone response HSF1 controls hepatic bioenergetics and protein homeostasis." in: The Journal of cell biology, Vol. 216, Issue 3, pp. 723-741, (2017) (PubMed).

Details zu NDUFS3

Target: NDUFS3 (NADH Dehydrogenase (Ubiquinone) Fe-S Protein 3, 30kDa (NADH-Coenzyme Q Reductase) (NDUFS3))

Andere Bezeichnung: NDUFS3 (NDUFS3 Produkte)

Synonyme: CI-30 antikoerper, 0610010M09Rik antikoerper, CI-30kD antikoerper, GB15355 antikoerper, zgc:112520 antikoerper, NADH:ubiquinone oxidoreductase core subunit S3 antikoerper, NADH dehydrogenase (ubiquinone) Fe-S protein 3 antikoerper, NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial antikoerper, NADH:ubiquinone oxidoreductase core subunit S3 S homeolog antikoerper, NADH dehydrogenase (ubiquinone) Fe-S protein 3, (NADH-coenzyme Q reductase) antikoerper, NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) antikoerper, NDUFS3 antikoerper, Ndufs3 antikoerper, ndufs3 antikoerper, LOC411411 antikoerper, ndufs3.S antikoerper, LOC100228726 antikoerper

Hintergrund: This gene encodes one of the iron-sulfur protein (IP) components of mitochondrial NADH:ubiquinone oxidoreductase (complex I). Mutations in this gene are associated with Leigh syndrome resulting from mitochondrial complex I deficiency.

Cellular Localization: Mitochondrion inner membrane

Molekulargewicht: 30 kDa

Gen-ID: 4722

Pathways: Negative Regulation of intrinsic apoptotic Signaling