MYL2 Antikörper
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- Target Alle MYL2 Antikörper anzeigen
- MYL2 (Myosin, Light Chain 2, Regulatory, Cardiac, Slow (MYL2))
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Reaktivität
- Maus, Ratte, Zebrafisch (Danio rerio)
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Wirt
- Kaninchen
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Klonalität
- Monoklonal
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Konjugat
- Dieser MYL2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Kreuzreaktivität
- Maus, Ratte, Zebrafisch (Danio rerio)
- Aufreinigung
- Purified by Protein A.
- Immunogen
- Human Myosin Light Chain 2 between 150-250 amino acids
- Klon
- 10B7
- Isotyp
- IgG
- Top Product
- Discover our top product MYL2 Primärantikörper
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- Applikationshinweise
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WB 1:300-5000
IHC-P 1:200-400
IF(ICC) 1:50-200
IHC() - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C for 12 months.
- Haltbarkeit
- 12 months
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- Target
- MYL2 (Myosin, Light Chain 2, Regulatory, Cardiac, Slow (MYL2))
- Andere Bezeichnung
- Myosin Light Chain 2 (MYL2 Produkte)
- Synonyme
- CMH10 antikoerper, MLC2 antikoerper, 2410014J02Rik antikoerper, MLC-2 antikoerper, Mlc2 antikoerper, MLC-2v antikoerper, Mlc2v antikoerper, Mylpc antikoerper, Mlc-2 antikoerper, myl2 antikoerper, zgc:136848 antikoerper, XMLC2 antikoerper, cmh10 antikoerper, mlc2 antikoerper, G2 antikoerper, MLC-2A antikoerper, MLC2V antikoerper, myosin light chain 2 antikoerper, myosin light chain, phosphorylatable, fast skeletal muscle antikoerper, myosin, light polypeptide 2, regulatory, cardiac, slow antikoerper, myosin, light chain 2b, regulatory, cardiac, slow antikoerper, myosin light chain 2 S homeolog antikoerper, myosin, light chain 2, regulatory, cardiac, slow antikoerper, MYL2 antikoerper, Mylpf antikoerper, Myl2 antikoerper, myl2b antikoerper, myl2.S antikoerper
- Hintergrund
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Synonyms: Myosin regulatory light chain 2, ventricular/cardiac muscle isoform, Cardiac myosin light chain 2, Myosin light chain 2, slow skeletal/ventricular muscle isoform, Ventricular myosin light chain 2, MLC-2, MLC-2v, MLC-2s/v, MYL2
Background: Contractile protein that plays a role in heart development and function (PubMed:10409661). Following phosphorylation, plays a role in cross-bridge cycling kinetics and cardiac muscle contraction by increasing myosin lever arm stiffness and promoting myosin head diffusion, as a consequence of the increase in maximum contraction force and calcium sensitivity of contraction force. These events altogether slow down myosin kinetics and prolong duty cycle resulting in accumulated myosins being cooperatively recruited to actin binding sites to sustain thin filament activation as a means to fine-tune myofilament calcium sensitivity to force (By similarity) (PubMed:22426213, PubMed:16908724, PubMed:10409661). During cardiogenesis plays an early role in cardiac contractility by promoting cardiac myofibril assembly (PubMed:9422794).
- Gen-ID
- 17906
- UniProt
- P51667
- Pathways
- Myometrial Relaxation and Contraction
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