LC3B Antikörper

Produktnummer ABIN6943909

Produktdetails anti-LC3B Antikörper

Target: LC3B (MAP1LC3B) (Microtubule-Associated Protein 1 Light Chain 3 beta (MAP1LC3B))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser LC3B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: Recombinant protein

Klon: 1C4

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu LC3B

Target: LC3B (MAP1LC3B) (Microtubule-Associated Protein 1 Light Chain 3 beta (MAP1LC3B))

Andere Bezeichnung: LC3B (MAP1LC3B Produkte)

Synonyme: ATG8F antikoerper, LC3B antikoerper, MAP1A/1BLC3 antikoerper, MAP1LC3B-a antikoerper, Map1lc3 antikoerper, Mpl3 antikoerper, zbs559 antikoerper, 1010001C15Rik antikoerper, Atg8 antikoerper, LC3b antikoerper, zgc:56434 antikoerper, wu:fb60g11 antikoerper, map1lc3b antikoerper, MGC76283 antikoerper, MAP1LC3B antikoerper, microtubule associated protein 1 light chain 3 beta antikoerper, microtubule-associated protein 1 light chain 3 beta antikoerper, microtubule associated protein 1 light chain 3 beta L homeolog antikoerper, MAP1LC3B antikoerper, Map1lc3b antikoerper, map1lc3b antikoerper, map1lc3b.L antikoerper

Hintergrund:

Synonyms: Microtubule-associated proteins 1A/1B light chain 3B, Autophagy-related protein LC3 B, Autophagy-related ubiquitin-like modifier LC3 B, MAP1 light chain 3-like protein 2, MAP1A/MAP1B light chain 3 B, Microtubule-associated protein 1 light chain 3 beta, MAP1A/MAP1B LC3 B, MAP1LC3B

Background: Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes). Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation. Promotes primary ciliogenesis by removing OFD1 from centriolar satellites via the autophagic pathway.

Gen-ID: 81631

UniProt: Q9GZQ8

Pathways: Autophagie