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PD-L1 Antikörper (AA 39-191)

PD-L1 Reaktivität: Human FACS, IHC, ELISA, IF, Coat Wirt: Maus Monoclonal PDL1-2743 unconjugated
Produktnummer ABIN6939568
  • Target Alle PD-L1 Antikörper anzeigen
    PD-L1 (CD274 (PD-L1))
    Bindungsspezifität
    • 29
    • 16
    • 15
    • 13
    • 11
    • 11
    • 9
    • 7
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 39-191
    Reaktivität
    • 171
    • 108
    • 63
    • 7
    • 6
    • 5
    • 5
    • 1
    • 1
    Human
    Wirt
    • 127
    • 62
    • 17
    • 4
    • 4
    • 1
    Maus
    Klonalität
    • 108
    • 105
    • 2
    Monoklonal
    Konjugat
    • 99
    • 16
    • 13
    • 11
    • 9
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Dieser PD-L1 Antikörper ist unkonjugiert
    Applikation
    • 139
    • 104
    • 60
    • 40
    • 38
    • 28
    • 17
    • 17
    • 16
    • 15
    • 10
    • 7
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Coating (Coat)
    Aufreinigung
    Purified by Protein A/G
    Immunogen
    Recombinant fragment of human CD274 protein (around aa 39-191) (exact sequence is proprietary)
    Klon
    PDL1-2743
    Isotyp
    IgG2b kappa
    Top Product
    Discover our top product PD-L1 Primärantikörper
  • Applikationshinweise

    Positive Control: Heart, Placenta, Spleen or Tonsil (IHC). Jurkat cells (IF/FACS).

    Known Application: ELISA (For coating, order antibody without BSA),Flow Cytometry (1-2 μg/mL),Immunofluorescence (1-2 μg/mL),Optimal dilution for a specific application should be determined.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-80 °C
    Informationen zur Lagerung
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Haltbarkeit
    24 months
  • Target
    PD-L1 (CD274 (PD-L1))
    Andere Bezeichnung
    CD274 (PD-L1 Produkte)
    Synonyme
    B7-H antikoerper, B7H1 antikoerper, PD-L1 antikoerper, PDCD1L1 antikoerper, PDCD1LG1 antikoerper, PDL1 antikoerper, A530045L16Rik antikoerper, B7h1 antikoerper, Pdcd1l1 antikoerper, Pdcd1lg1 antikoerper, Pdl1 antikoerper, RGD1566211 antikoerper, CD274 molecule antikoerper, CD274 antigen antikoerper, programmed cell death 1 ligand 2 antikoerper, CD274 antikoerper, Cd274 antikoerper, PDCD1LG2 antikoerper
    Hintergrund
    PD-L1 is a checkpoint regulator in immune cells, it is expressed on immune or non-hematopoietic cells. Expression of the protein is seen during pregnancy where it has a role in suppressing the immune system. PD-L1 induces an inhibitory signal in activated T-cells and promotes T-cell apoptosis. It is overexpressed in a number of different cancers where it is believed to play a significant role in the cancer s ability to evade the immune system.
    Molekulargewicht
    37-50kDa
    Gen-ID
    29126
    UniProt
    Q9NZQ7
    Pathways
    Cancer Immune Checkpoints
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