Rekombinanter MYH11 Antikörper

Produktnummer ABIN6937996

Produktdetails anti-MYH11 Antikörper

Target: MYH11 (Myosin Heavy Chain 11, Smooth Muscle (MYH11))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser MYH11 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Spezifität: Smooth muscle myosin heavy chain (SM-MHC) is a cytoplasmic structural protein, which is a major component of the contractile apparatus in smooth muscle cells. Expression of smooth muscle myosin is developmentally regulated, appearing early in smooth muscle development, and is specific for smooth muscle development. Two isoforms of smooth muscle myosin heavy chain have been identified, designated MHC-1 and MHC-2. The antibody may be useful for the study of breast tumors as the presence of an intact layer of myoepithelial cells is an important feature, which may distinguish benign breast lesions and carcinoma in situ from invasive tumors.

Kreuzreaktivität (Details): Human. Cow. Pig. Dog. Cat. Rabbit. Rat. Guinea Pig. Chicken.

Aufreinigung: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Recombinant full-length human MYH11 protein

Klon: MYH11-2303R

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

Positive_Control: Uterus or normal breast.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Haltbarkeit: 24 months

Details zu MYH11

Target: MYH11 (Myosin Heavy Chain 11, Smooth Muscle (MYH11))

Andere Bezeichnung: MYH11 (MYH11 Produkte)

Synonyme: AV071570 antikoerper, SM1 antikoerper, SM2 antikoerper, smMHC antikoerper, AAT4 antikoerper, FAA4 antikoerper, SMHC antikoerper, SMMHC antikoerper, myosin antikoerper, myh11 antikoerper, myosin, heavy polypeptide 11, smooth muscle antikoerper, myosin heavy chain 11 antikoerper, myosin, heavy chain 11, smooth muscle antikoerper, myosin, heavy chain 11a, smooth muscle antikoerper, Myh11 antikoerper, MYH11 antikoerper, myh11a antikoerper

Hintergrund: AAT4, Myosin heavy chain 11 (MYH11), Myosin heavy chain 11 smooth muscle, Smooth muscle myosin heavy chain 11, Myosin-11, SM1, SM2, SMHC, SMMHC,Smooth Muscle Myosin Heavy Chain (SM-MHC)
Cellular localisation: Cytoplasmic

Molekulargewicht: 205kDa (MHC-1) and 200kDa (MHC-2)

Gen-ID: 4629, 460109

UniProt: P35749