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MYH11 Antikörper

MYH11 Reaktivität: Human IHC, IF, WB Wirt: Kaninchen Monoclonal unconjugated
Produktnummer ABIN7268745
  • Target Alle MYH11 Antikörper anzeigen
    MYH11 (Myosin Heavy Chain 11, Smooth Muscle (MYH11))
    Reaktivität
    • 40
    • 20
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    Human
    Wirt
    • 35
    • 8
    Kaninchen
    Klonalität
    • 23
    • 20
    Monoklonal
    Konjugat
    • 26
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Dieser MYH11 Antikörper ist unkonjugiert
    Applikation
    • 14
    • 12
    • 11
    • 8
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Immunofluorescence (IF), Western Blotting (WB)
    Verwendungszweck
    SMMHC/MYH11 Rabbit mAb
    Kreuzreaktivität
    Human, Maus, Ratte
    Produktmerkmale
    Monoclonal Antibodies
    Aufreinigung
    Affinity purification
    Immunogen
    A synthesized peptide derived from human SMMHC/SMMHC/MYH11
    Isotyp
    IgG
  • Applikationshinweise
    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    MYH11 (Myosin Heavy Chain 11, Smooth Muscle (MYH11))
    Andere Bezeichnung
    MYH11 (MYH11 Produkte)
    Synonyme
    AV071570 antikoerper, SM1 antikoerper, SM2 antikoerper, smMHC antikoerper, AAT4 antikoerper, FAA4 antikoerper, SMHC antikoerper, SMMHC antikoerper, myosin antikoerper, myh11 antikoerper, myosin, heavy polypeptide 11, smooth muscle antikoerper, myosin heavy chain 11 antikoerper, myosin, heavy chain 11, smooth muscle antikoerper, myosin, heavy chain 11a, smooth muscle antikoerper, Myh11 antikoerper, MYH11 antikoerper, myh11a antikoerper
    Hintergrund
    The protein encoded by this gene is a smooth muscle myosin belonging to the myosin heavy chain family. The gene product is a subunit of a hexameric protein that consists of two heavy chain subunits and two pairs of non-identical light chain subunits. It functions as a major contractile protein, converting chemical energy into mechanical energy through the hydrolysis of ATP. The gene encoding a human ortholog of rat NUDE1 is transcribed from the reverse strand of this gene, and its 3' end overlaps with that of the latter. The pericentric inversion of chromosome 16 [inv(16)(p13q22)] produces a chimeric transcript that encodes a protein consisting of the first 165 residues from the N terminus of core-binding factor beta in a fusion with the C-terminal portion of the smooth muscle myosin heavy chain. This chromosomal rearrangement is associated with acute myeloid leukemia of the M4Eo subtype. Alternative splicing generates isoforms that are differentially expressed, with ratios changing during muscle cell maturation. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008],AAT4, FAA4, SMHC, SMMHC,Cardiovascular,Cardiovascular Markers,Cardiovascular Markers_Smooth Muscle Cells,Cell Biology & Developmental Biology,Cytoskeleton,Cytoskeleton_Motor Proteins,Heart,Heart_Contractility,Signal Transduction,Stem Cells,MYH11
    Molekulargewicht
    250kDa
    Gen-ID
    4629
    UniProt
    P35749
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