IFNA1 Antikörper

Produktnummer ABIN6937476

Produktdetails anti-IFNA1 Antikörper

Target: IFNA1 (Interferon, alpha 1 (IFNA1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IFNA1 Antikörper ist unkonjugiert

Applikation: Immunofluorescence (IF), Flow Cytometry (FACS)

Spezifität: This MAb is specific for human interferon alpha 1 and does not cross react with human interferon alpha 2. Interferons are widely used therapeutic agents because of their anti-tumor and anti-viral effects and because of their modulatory effects on the immune system. These cytokines produce their effects by binding to the Type 1 Interferon- & Receptor (IFNAR1). Down regulation of this receptor plays a key role in determining the magnitude and duration of cytokine signaling. This down regulation is influenced by phosphorylation of Serine 535 and 539 in the IFNAR1.

Kreuzreaktivität (Details): Human.

Aufreinigung: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Purified recombinant human IFN-alpha1

Klon: Feb-52

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise:

Known_Application: Flow Cytometry (0.5-1 μg/million cells), ,Immunofluorescence (0.5-1 μg/mL), ,Optimal dilution for a specific application should be determined.

Positive_Control: Stimulated human peripheral blood mononuclear cells

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Haltbarkeit: 24 months

Details zu IFNA1

Target: IFNA1 (Interferon, alpha 1 (IFNA1))

Andere Bezeichnung: IFNA1 (IFNA1 Produkte)

Synonyme: IFL antikoerper, IFN antikoerper, IFN-ALPHA antikoerper, IFN-alphaD antikoerper, IFNA13 antikoerper, IFNA@ antikoerper, Ifa1 antikoerper, IFN-ALPHA-1 antikoerper, IFN1@ antikoerper, IFNA1 antikoerper, IFN-alpha antikoerper, IFN-gamma antikoerper, IFNA antikoerper, IFNA2 antikoerper, IFNA6 antikoerper, IFN-alpha1 antikoerper, interferon alpha 13 antikoerper, interferon alpha 1 antikoerper, interferon, alpha 1 antikoerper, interferon, alpha 13 antikoerper, interferon antikoerper, interferon-alpha 1 antikoerper, interferon, alpha, leukocyte antikoerper, interferon-alpha-14 antikoerper, IFNA13 antikoerper, IFNA1 antikoerper, Ifna1 antikoerper, ifna1 antikoerper, IFNA3 antikoerper, IFN-ALPHA-14 antikoerper

Hintergrund: IFN alpha, IFN alpha 1/13, IFN alpha 1b, Interferon alpha 13 (IFNA13), Interferon alpha leukocyte (IFL), Interferon alpha-1/13 (IFN-alpha-1/13), Interferon alpha-D (IFN alphaD), Interferon alpha1 (IFNA1), LeIF D,Interferon alpha-1 (IFNA1)
Cellular localisation: Cytoplasmic & Extracellular (Secreted)

Molekulargewicht: 16-27kDa

Gen-ID: 3439

UniProt: P01562

Pathways: JAK-STAT Signalweg, Hepatitis C