CYP2E1 Antikörper (C-Term)
-
- Target Alle CYP2E1 Antikörper anzeigen
- CYP2E1 (Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 (CYP2E1))
-
Bindungsspezifität
- C-Term
-
Reaktivität
- Human
-
Wirt
- Maus
-
Klonalität
- Monoklonal
-
Konjugat
- Dieser CYP2E1 Antikörper ist unkonjugiert
-
Applikation
- Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- Spezifität
- This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases, which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is induced by ethanol, the diabetic state, and starvation. The enzyme metabolizes both endogenous substrates, such as ethanol, acetone, and acetal, as well as exogenous substrates including benzene, carbon tetrachloride, ethylene glycol, and nitrosamines, which are pre-mutagens found in cigarette smoke. Due to its many substrates, this enzyme may be involved in such varied processes as gluconeogenesis, hepatic cirrhosis, diabetes, and cancer.
- Kreuzreaktivität (Details)
- Human.
- Aufreinigung
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogen
- Ovalbumin-conjugated synthetic peptide HIGFGCIPPR (C-terminal sequence)
- Klon
- M12P4H2
- Isotyp
- IgG1 kappa
- Top Product
- Discover our top product CYP2E1 Primärantikörper
-
-
- Applikationshinweise
-
Known_Application: Immunohistochemistry (Formalin-fixed) (0.1-0.2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: HepG2 cells. Liver.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Konzentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Konservierungsmittel
- Azide free
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Haltbarkeit
- 24 months
-
- Target
- CYP2E1 (Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 (CYP2E1))
- Andere Bezeichnung
- CYP2E1 (CYP2E1 Produkte)
- Synonyme
- CYP2E1 antikoerper, CYP2E antikoerper, CYPIIE1 antikoerper, CPE1 antikoerper, P450-J antikoerper, P450C2E antikoerper, Cyp2e antikoerper, cytochrome P450, family 2, subfamily E, polypeptide 1 antikoerper, cytochrome P450 2E1 antikoerper, cytochrome P450 2E1-like antikoerper, cytochrome P450 family 2 subfamily E member 1 antikoerper, cytochrome P450, family 2, subfamily e, polypeptide 1 antikoerper, CYP2E1 antikoerper, PTRG_07411 antikoerper, LOC100342572 antikoerper, LOC100727914 antikoerper, LOC101843716 antikoerper, Cyp2e1 antikoerper
- Hintergrund
-
4-nitrophenol 2-hydroxylase, CPE1, CYP2Ecytochrome P450 2E1, CYPIIE1, cytochrome P450, family 2, subfamily E, polypeptide 1, cytochrome P450, subfamily IIE (ethanol-inducible), polypeptide 1 , Cytochrome P450-J, EC 1.14.13, EC 1.14.13.n7, EC 1.14.14.1, flavoprotein-linked monooxygenase, microsomal monooxygenase, P450C2E, P450-J, xenobiotic monooxygenase,Cytochrome p450
Cellular localisation: Endoplasmic reticulum membrane. Microsome membrane. - Molekulargewicht
- ~50-55kDa
- Gen-ID
- 1571, 12907
- UniProt
- P05181
-